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Device for electrospinning three-dimensional controlled structure of nanofibers

An electrospun nanofiber, three-dimensional technology, applied in the field of electrospun nanofiber three-dimensional controllable structure device, can solve the problems of complex three-dimensional structure, low technical efficiency, and inaccessibility

Inactive Publication Date: 2012-08-15
XIAMEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Of course, other methods such as conductive rings, sharp-edged rotating conductive aluminum disk collectors, rotating drum collectors, double collection rings, and water eddies can also orient nanofibers, but they are mainly used to make yarns (yarn) , the three-dimensional structure of the complex shape cannot be obtained
[0005] There are few preparation methods for the three-dimensional structure of nanofibers, mainly (1) using a flat collection plate / net to collect nanofibers to form a three-dimensional structure (Yuan Ji, Kaustabh Ghosh, Xiao Zheng Shu, et al.Biomaterials 27(2006) 3782-3792) , this method cannot directly obtain a three-dimensional nanofiber structure; (2) construct a three-dimensional cartilage tissue bioscaffold structure through a combination of rapid prototyping and electrospinning technology, in which the three-dimensional structure of rapid prototyping large-diameter fibers is used to build a high-strength framework (Lorenzo Moroni , Roka Schotel, Doreen Hamann, Joost R.de Wijn, and Clemens A.van Blitterswijk Adv.Funct.Mater.2008, 18, 53-60), can manufacture complex shape structures, but the technology is very inefficient and cannot be applied to Batch manufacturing of structural parts and manufacturing of large-area free-form surfaces; (3) The rotary jet spinning method can prepare well-oriented circular three-dimensional nanofiber bioscaffolds on a circular collector, and the three-dimensional structure can only be a circular body. Not easily scalable (Mohammad Reza Badrossamay, Holly Alice McIlwee, Josue A. Goss, Kevin Kit Parker. Nano Lett. 2010, 10, 2257-2261)
Chinese researchers use a simple tubular electrode structure as a mold to produce a hollow tubular three-dimensional nanofiber structure, but the prepared hollow tube three-dimensional structure is relatively simple and fixed, and can achieve a small area (Daming Zhang and Jiang Chang, Nano Lett. , 2008, 8, 3283-3287)

Method used

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  • Device for electrospinning three-dimensional controlled structure of nanofibers
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  • Device for electrospinning three-dimensional controlled structure of nanofibers

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Embodiment Construction

[0022] see figure 1 and 2 , the embodiment of the present invention is provided with DC high-voltage power supply 1, nozzle array support plate 2, spinning nozzle array 3, probe array 4, polytetrafluoroethylene insulating substrate 5 with equidistant holes, controller 6 (using single-chip microcomputer), Auxiliary DC high-voltage power supply 7, guide rail 8 and precision injection pump 9.

[0023]The positive pole of the DC high-voltage power supply 1 (30kV) is electrically connected to the spinning nozzle array 3, and the negative pole of the DC high-voltage power supply 1 is connected to the negative pole of the auxiliary DC high-voltage power supply 7 (10kV) and grounded. The precision syringe pump 9 communicates with the spinning nozzle array 3 through a plastic hose (delivery tube), and provides the spinning nozzle array 3 with a solution with a flow rate of 0.3-20 L / h. The distance between the nozzles of the spinneret array 3 and the polytetrafluoroethylene insulating...

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Abstract

The invention discloses a device for electrospinning a three-dimensional controlled structure of nanofibers, and relates to a device for electrospinning the nanofibers. The device is provided with a direct-current high-voltage power supply, a flow controller, a spinning spray head array, a spray head array supporting plate, a guide rail, a probe array, a probe array substrate, a controller and anauxiliary direct-current high-voltage power supply, wherein the anode of the direct-current high-voltage power supply is electrically connected with the spinning spray head array; the cathode of direct-current high-voltage power supply is electrically connected with the cathode of the auxiliary direct-current high-voltage power supply and is grounded; the flow controller is communicated with the spray heads of the spinning spray head array through a flow conveying pipe; the spinning spray head array is arranged on the spray head array supporting plate; the spray head array supporting plate isin movable fit with the guide rail; the probe array is arranged on the probe array substrate and is positioned below the spinning spray head array; the control signal output end of the controller is electrically connected with the probes of the probe array respectively; and the output end of the auxiliary direct-current high-voltage power supply is connected with the power supply input end of thecontroller. A mold is not needed, production efficiency is high, and the external shape and internal porosity and pore size of the nanofibers can be freely adjusted.

Description

technical field [0001] The invention relates to a nanofiber electrospinning device, in particular to an electrospun nanofiber three-dimensional controllable structure device. Background technique [0002] The three-dimensional structure based on nanofibers is widely used in composite materials, tissue engineering, biological scaffolds, energy and other fields. From the perspective of structural features, there are mainly large-area smooth components (such as composite aircraft wings and automobile outer coverings, etc.), complex three-dimensional shape structures (such as composite material aircraft landing gear rear struts and automobile parts), and complex three-dimensional shapes. And the inside has micro-nano porosity and pore size required structure (such as bone or blood vessel biological scaffold) and other forms. The three-dimensional structure with porous interior and a certain porosity and micro-nano pore size is used as a biological scaffold to facilitate the mig...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): D01D5/00D01D5/247D01D13/00
Inventor 吴德志孙道恒詹瞻胡兴旺郑高峰
Owner XIAMEN UNIV
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