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Quality control method for Zengguang capsules

A quality control method and capsule technology, which can be used in capsule delivery, medical preparations containing active ingredients, measuring devices, etc., and can solve problems such as poor operational safety, harmful to human health, and strong liver toxicity.

Inactive Publication Date: 2011-11-09
ZHENGZHOU FURUITANG PHARMA
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  • Abstract
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  • Claims
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Problems solved by technology

The twelfth phase of volume 16 of Shi Zhen Guo Yi Guo Yao in 2005 reported the method for the content of ferulic acid in Zengguang Tablets by high performance liquid chromatography, which has the following defects (1) high waste of energy for reflux extraction and poor operation safety; 2) Take chloroform as the extraction solvent, which has strong hepatotoxicity and is harmful to human health; (3) the reproducibility of the measurement results is poor

Method used

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  • Quality control method for Zengguang capsules

Examples

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Embodiment 1

[0053] Example 1: Take 200g of Chinese herbal medicine Lycium barbarum, 100g of Codonopsis pilosula, 100g of Chinese angelica, 36g of Radix Ophiopogonis, 30g of Poria cocos, 24g of Alisma, 24g of Cortex Moutan, 18g of Schisandra chinensis, 18g of Shichangpu, 18g of polygala (licorice water system), and ten of the above raw materials To taste, take Schisandra chinensis, Shichangpu, Poria cocos, polygala, and Codonopsis 20g, mix and grind them into fine powder, and sieve; the remaining Dang participative and other five flavors such as Alisma and other five flavors are decocted twice, and the decoction is combined, filtered, and the filtrate is concentrated into Thick paste, add powders such as schisandra chinensis, mix evenly, dry, pulverize, pack into capsules, make 1000 capsules, each capsule 0.3g; The quality control method of this medicine comprises the following steps:

[0054] (1), measure ferulic acid (C 18 h 21 o 3 ) content:

[0055] a. Chromatographic conditions: us...

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Abstract

The invention provides a new quality control method for Zengguang capsules and overcomes the drawbacks of the prior art. In the invention, the content of ferulic acid in the compound preparation, namely the Zengguang capsules, is measured by high efficiency liquid chromatography; and the thin-layer chromatography identification of medlar, which is the main medicine of the compound preparation, and medicinal materials including Codonopsis pilosula and Schisandra chinensis is performed, so the accuracy and advancement of the quality control method of the compound preparation are ensured, and the product quality of the Zengguang capsules can be controlled more effectively.

Description

technical field [0001] The invention relates to a quality control method of Zengguang Capsule, a compound preparation of traditional Chinese medicine. technical background [0002] The traditional Chinese medicine compound preparation Zengguang Capsule is composed of 200g of Chinese herbal medicine Lycium barbarum, 100g of Codonopsis pilosula, 100g of Angelica sinensis, 36g of Radix Ophiopogon japonicus, 30g of Poria cocos, 24g of Alisma, 24g of Cortex Moutan, 18g of Schisandra chinensis, 18g of Shichangpu, and 18g of polygala (licorice water system). The raw materials were made into 1000 grains in total. Lycium barbarum is the main medicinal taste in the prescription, which is the dry and mature fruit of Lycium barbarum L., a plant of the Solanaceae family, which has the effects of nourishing the liver and kidney, benefiting energy and improving eyesight; Codonopsis pilosula (Franch.) Nannf. Codonopsis pilosula Nannf.var.modesta (Nannf.) L.T.Shen or the dried root of Codon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/48A61P27/10G01N30/02G01N30/90
Inventor 高超旭周毅擎王少龙
Owner ZHENGZHOU FURUITANG PHARMA
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