Confocal laser micro-endoscope

Abstract

The invention relates to a confocal laser micro-endoscope, which comprises a light source lighting system, a confocal scanning unit, a coupling lens group, an image transmission optical fiber, an object lens, an optical fiber confocal spectroscopic analysis system and an image analysis and reconstruction system. A laser light source provided by the light source lighting system enters the confocalscanning unit, is coupled into the image transmission optical fiber by the coupling lens group in the confocal scanning unit to be transmitted to the object lens, and then is emitted onto a detectionsample, and fluorescence reflected on the sample is transmitted into the optical fiber confocal spectroscopic analysis system through the object lens, the image transmission optical fiber and the confocal scanning unit, and then completes the image reconstruction by the image analysis and reconstruction system in a host. The image resolution of biological images is improved, and the confocal laser microendoscope has the advantages of high image resolution, small physical size of a probe, real-time detection and the like.

Description

technical field [0001] The invention belongs to the technical field of biomedical device manufacturing, in particular to a laser confocal microendoscope for biomedical cell detection technology. Background technique [0002] In modern medicine, biopsy is an important means for clinical diagnosis of tumors and evaluation of surgical effects. According to statistical data, there are hundreds of millions of biopsy diagnoses in the world every year. The general process is to take out biopsy sections in the body by puncture and other methods, and then make pathological diagnosis under a microscope. Each diagnosis takes several days, and medical costs higher. [0003] At the same time, the current medical imaging technologies such as X-ray film, CT and MRI have become the routine means of disease diagnosis, greatly speeding up the diagnosis time. However, in the early stage of cancer, the mass is small and not obvious, and the existing imaging technology is difficult to achieve ...

AI Technical Summary

Problems solved by technology

The disadvantage is that the physical performance requirements of the equipment are greatly improved, which is not conducive to the popularization of high-performance imaging equipment

The accuracy and sensitivity of confocal endoscopy in diagnosing various diseases have reached a certain level, but it is still in its infancy in China

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