Chinese medicine composite and preparation method and medicinal preparation thereof

A technology of traditional Chinese medicine preparations and compositions, which is applied in the field of traditional Chinese medicine compositions and their preparation methods and preparations, which can solve the problems of low drug efficacy, failure to meet the treatment requirements of cancer patients, and failure of anti-tumor methods to suppress tumors, and achieve recovery. and immune function, enhance the activity, enhance the effect of immune function

Active Publication Date: 2012-04-11
DIAOYUTAI MEDICAL GRP JILIN TIANQIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this single anti-tumor method cannot achieve the best tumor-inhibiting effect, making these drugs less effective and unable to meet the treatment requirements of cancer patients

Method used

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  • Chinese medicine composite and preparation method and medicinal preparation thereof
  • Chinese medicine composite and preparation method and medicinal preparation thereof
  • Chinese medicine composite and preparation method and medicinal preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1: prepare Chinese medicine composition of the present invention

[0027] 1. Preparation method

[0028] Take 20g of red lucidum and grind it into a powder with a diameter of 2000μm, add water to soak for 12 hours, decoct for 3 hours, then filter, add water to the filter residue and decoct for 3 hours, then filter, combine the filtrates obtained twice, and concentrate at 80°C to a relative density of 1.36 , and then dried and crushed into a powder with a diameter of 180 μm to obtain 1.7 g of Ganoderma lucidum extract, which was mixed with 0.27 g of ginsenoside Rh2.

[0029] 2. Tumor suppression test

[0030] Tumor cells: human liver cancer cell line BeI-7404, prostate cancer cell line PC-3M, human breast cancer cell line MCF-7, esophageal cancer cell line Eca-190, human laryngeal cancer cell line Hep-2, mouse melanoma cells Strain B16 was purchased from Dalian Institute of Chemical Physics;

[0031] Tested drug and grouping: the traditional Chinese medicin...

Embodiment

[0041] 1. Preparation method

[0042] Take 24g flat-covered Ganoderma lucidum and crush it into a powder with a diameter of 2000μm, add water to soak for 12 hours, decoct for 3 hours, then filter, add water to the filter residue and decoct for 3 hours, then filter, combine the filtrates obtained twice, and concentrate at 80°C to relative density 1.38, then dried and crushed into a powder with a diameter of 180 μm to obtain 1.8 g of Ganoderma lucidum extract, which was mixed with 0.31 g of ginsenoside Rh2 by the incremental dilution method.

[0043] 2. Tumor suppression test

[0044] Tumor cells: human liver cancer cell line BeI-7404, prostate cancer cell line PC-3M, human breast cancer cell line MCF-7, esophageal cancer cell line Eca-190, human laryngeal cancer cell line Hep-2, mouse melanoma cells Strain B16 was purchased from Dalian Institute of Chemical Physics;

[0045]Tested drug and grouping: the traditional Chinese medicine composition prepared according to the prepar...

Embodiment 3

[0055] 1. Preparation method

[0056] Take 16g of red lucidum and crush it into a powder with a diameter of 2000μm, add water to soak for 12 hours, decoct for 3 hours and then filter, add water to the filter residue and decoct for 3 hours again, then filter, combine the filtrate obtained twice, and concentrate at 80°C to a relative density of 1.35 , and then dried and crushed into a powder with a diameter of 180 μm to obtain 1.3 g of Ganoderma lucidum extract, which was mixed with 0.23 g of ginsenoside Rh2 by the incremental dilution method.

[0057] 2. Tumor suppression test

[0058] Tumor cells: human liver cancer cell line BeI-7404, prostate cancer cell line PC-3M, human breast cancer cell line MCF-7, esophageal cancer cell line Eca-190, human laryngeal cancer cell line Hep-2, mouse melanoma cells Strain B16 was purchased from Dalian Institute of Chemical Physics;

[0059] Tested drug and grouping: the traditional Chinese medicine composition prepared according to the pre...

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Abstract

The invention relates to the field of Chinese medicines and discloses a Chinese medicine composite and a preparation method and a medicinal preparation thereof. The Chinese medicine composite comprise the following raw materials in parts by weight: 11.5-15.5 parts of ginsenoside Rh2 and 800-1200 parts of lucid ganoderma. The preparation method comprises the following steps of: preparing 800-1200 parts by weight of lucid ganoderma, soaking in water for 12 hours, decocting for 3 hours and then filtering; adding water in filtered residue and decocting for 3 hours, and then filtering; mixing filtrates obtain in the former two steps and concentrating at 80 DEG C till the relative density is 1.35-1.38; and then drying and crushing into powder and finally uniformly mixing the powder with 11.5-15.5 parts of ginsenoside Rh2 to obtain the Chinese medicine composite. The Chinese medicine composite and a medicinal preparation thereof are compounded from lucid ganoderma extract, which is obtained through decocting lucid ganoderma with water, and ginsenoside Rh2, the two components complement each other's advantages and have mutual promotion effect; therefore, the activity for inhibiting tumors is improved and synergistic effect on tumor inhibition is achieved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition and a preparation method and preparation thereof. Background technique [0002] Malignant tumors are what we often call cancer. The basic unit of cancer lesions is cancer cells. Most cells in the human body can proliferate, but this hyperplasia is limited, while the proliferation of cancer cells is endless, which consumes a lot of nutrients in the patient's body. At the same time, cancer cells can release a variety of toxins, causing the body to produce a series of symptoms. If it is not discovered and treated in time, it can also be transferred to other parts of the body to grow and multiply, eventually leading to emaciation, weakness, anemia, loss of appetite, fever, and impaired organ function. [0003] Malignant tumor is one of the major diseases that seriously threaten human health, and 7 million people die from the dis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074A61P35/00A61K31/704
Inventor 段维和杨佐卿许绍英
Owner DIAOYUTAI MEDICAL GRP JILIN TIANQIANG PHARMA
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