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Normal-temperature preparation method of tarragon submicron powder and special bidirectional airflow sieving machine used by same

A powder capillary and air-flow sieve technology, which is applied in powder transportation, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of difficult to accurately control the maximum particle size of drugs, high bioavailability, and inability to produce continuously. Achieve the effects of being suitable for large-scale industrial production, simplifying the preparation process, and saving medicinal materials

Active Publication Date: 2012-04-11
HENAN KANGXING PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The purpose of the present invention is to provide a method for preparing ultrafine powder Yinchenhaosan at room temperature, which effectively solves the problems of high energy consumption, difficulty in accurately controlling the maximum particle size of the drug, inability to continuously produce, and much dust in the production process in the current production of Yinchenhaosan. , so that the prepared finished drug has the effects of fast onset of action, good curative effect, high bioavailability, and less clinical dosage

Method used

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  • Normal-temperature preparation method of tarragon submicron powder and special bidirectional airflow sieving machine used by same
  • Normal-temperature preparation method of tarragon submicron powder and special bidirectional airflow sieving machine used by same
  • Normal-temperature preparation method of tarragon submicron powder and special bidirectional airflow sieving machine used by same

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Embodiment Construction

[0033] Such as figure 1 , 2 Shown, the normal temperature preparation method of superfine powder Yinchenhao powder of the present invention comprises the following steps:

[0034] The first step is to select the decoction pieces of raw materials Capillary, Gardenia, and Rhubarb respectively; to dry naturally or until the moisture content is ≤10%;

[0035] The second step is to pulverize the above raw materials respectively at a temperature of 20° C. to 25° C. to obtain a coarse powder with a particle size of 60 to 80 meshes;

[0036] The 3rd step, the coarse powder gained in the 2nd step is mixed uniformly by the weight ratio of capillary vine: gardenia: rhubarb=8:4:3;

[0037] In the fourth step, first turn on the powder conveying fan 15, the induced draft fan 5, the blower 11, and the drive motor 8. The blowing pressure of the powder conveying fan 15 is 24kpa, and the blowing volume is 150m 3 / h; the induced air pressure of the induced draft fan 5 is 1000pa, and the ind...

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Abstract

The invention discloses a normal-temperature preparation method of tarragon submicron powder, which comprises: selecting Chinese herbal pieces of oriental wormwood, cape jasmine fruit and rheum officinale and drying the Chinese herbal pieces till the moisture content is less than or equal to 10 percent; grinding the raw material medicine at normal temperature and obtaining coarse powder; uniformly mixing coarse powder according to an oriental wormwood to cape jasmine fruit to rheum officinale ratio of 8:4:3, grinding the mixture into a rod mill, delivering the powder by wind to a special bidirectional airflow sieving machine to sieve the powder by a 500-mesh sieve, delivering undersize powder with a particle size of less than or equal to 25 micrometers to a cyclonic material collection device by an air flow generated by a draft fan, and collecting finished tarragon submicron powder; and collecting the oversize powder by using a funnel, and delivering the powder by a pipe to a rod millfor secondary circular grinding. The method has the advantages that: the whole preparation process is carried out at normal temperature, and the need of a low-temperature or special additional conditions is obviated; the particle size of the prepared finished medicine is less than or equal to 25 micrometers, and the cell wall breakage rate and bioavailability are improved greatly; and the bidirectional airflow sieving machine used in the method simplifies the preparation process of tarragon submicron powder.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a method for preparing superfine powder Yinchenhaosan at normal temperature; the invention also relates to a special two-way airflow sieving machine used in the method. Background technique [0002] At present, Yinchenhaosan used in livestock is mostly coarsely crushed powder, which has the disadvantages of large dose, rough dosage form, poor appearance, incomplete release of active ingredients, and low bioavailability, which seriously affects the quality and therapeutic effect of traditional Chinese medicine. Compared with other chemically synthesized drugs in the prevention and treatment of diseases, traditional Chinese medicine has the advantages of high safety, less toxic and side effects, more active ingredients, less harmful residues, more targets, and can play a combined effect, and is not easy to produce drug resistance. It can regulate the body's immunity and ...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61K9/14B02C23/20A61P31/04
Inventor 王伟伟张朝霞宋永奇马长宇贾艳华
Owner HENAN KANGXING PHARMA
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