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Donkey-hide gelatine raw powder and preparation method thereof

A collagen powder and collagen technology, which can be used in pharmaceutical formulations, powder delivery, unknown raw materials, etc., can solve the problems of easy moisture absorption, unfavorable preservation, and moisture absorption of powdered donkey-hide gelatin.

Active Publication Date: 2012-07-04
SHAN DONG DONG E E JIAO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, powdered donkey-hide gelatin is easy to absorb moisture and agglomerate, which is not conducive to preservation and is easy to mold
In order to solve the moisture absorption phenomenon of powdered donkey-hide gelatin, the drying technology of the stock solution (the state before condensation and drying of donkey-hide gelatin or the solution of donkey-hide gelatin) has been studied, and "donkey-hide gelatin powder" has been made. Inconvenient to carry and use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0026] Experimental Example 1 Comparison of the solubility of donkey-hide gelatin powder, donkey-hide gelatin granules, donkey-hide gelatin blocks, donkey-hide gelatin directly crushed granules, and donkey-hide gelatin spray-dried powder

[0027] Donkey-hide gelatin powder is prepared by the method of Example 4 of the present invention; donkey-hide gelatin granules, donkey-hide gelatin blocks, donkey-hide gelatin directly pulverized particles and donkey-hide gelatin spray-dried powder are all provided by Shandong Dong'e-hide gelatin Co., Ltd.

[0028] (1) Take respectively 20 grams of donkey-hide gelatin powder, donkey-hide gelatin granules, donkey-hide gelatin blocks, donkey-hide gelatin directly pulverized powder, and donkey-hide gelatin spray-dried powder;

[0029] (2) Add 400ml of water, then stir with a glass rod for 3 minutes;

[0030] (3) According to the solubility, only the donkey-hide gelatin powder of the present invention is completely dissolved, and all the other ...

experiment example 2

[0032] Experimental example 2 Density screening of donkey-hide gelatin solution obtained before vacuum drying and powder making of the present invention

[0033] (1) Prepare solutions A and B according to the method described in Example 4 of the present invention, mix solutions A and B, concentrate to a temperature of 15-30° C., and relative densities of 1.10, 1.12, 1.15, 1.20 and 1.26, respectively Donkey-hide gelatin solution, the donkey-hide gelatin solution of above-mentioned density is carried out vacuum continuous drying experiment under the process parameter described in embodiment 4 respectively;

[0034] (2) Experimental results have confirmed that the donkey-hide gelatin powder prepared by the donkey-hide gelatin solution with a relative density of 1.15 and 1.20 has the best solubility and can be completely dissolved in the same time, while the donkey-hide gelatin powder prepared by a donkey-hide gelatin solution with a density lower than 1.15 and higher than 1.20 Po...

experiment example 3

[0036] Time data screening of experimental example 3 vacuum continuous drying

[0037] In view of the fact that the conveyer belt of the vacuum continuous drying equipment is carried out at a uniform speed, at the same temperature, five time gradients were designed for experiments, which were 10 minutes, 15 minutes, 20 minutes, 25 minutes and 30 minutes, and the results confirmed that the collagen dried for 15 minutes The powder is relatively ideal in terms of color, appearance, shape, and solubility. The drying time determined by the drying test is 15 minutes per section.

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PUM

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Abstract

The invention relates to a medicine, in particular to donkey-hide gelatine raw powder for enriching the blood and a preparation method thereof. The donkey-hide gelatine raw powder disclosed by the invention comprises the following raw materials in composition and proportion: 80-140 parts by weight of donkey-hide gelatine, 10-18 parts by weight of crystal sugar, and 10-18 parts by weight of yellow wine. According to a pharmaceutical method, the donkey-hide gelatine raw powder disclosed by the invention can be prepared into a plurality of clinical dosage forms including the dosage form of oral preparations. The oral preparations are selected from one of troches, capsules, pills, granules, suspension, drop pills and oral liquid preparations.

Description

field of invention [0001] The invention relates to a medicine, in particular to donkey-hide collagen powder for blood enrichment and a preparation method thereof. Background technique [0002] Donkey-hide gelatin was first recorded in "Shen Nong's Materia Medica" in the Qin and Han Dynasties, and it was listed as the top grade. Li Shizhen's "Compendium of Materia Medica" in the Ming Dynasty called it the holy medicine for nourishing blood. Donkey-hide gelatin is still the drug of choice for enriching blood because of its definite curative effect. At present, there are innumerable medicines, health foods and foods that use donkey-hide gelatin as raw materials, and have been widely used. [0003] Donkey-hide gelatin is made from high-quality donkey skin with the unique groundwater in Dong'e County, Shandong Province, after decoction, boiling and drying. It has maintained a block shape for more than two thousand years. It has been confirmed by testing and analysis that the m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/36A61K9/14A61P7/06
Inventor 秦玉峰尤金花田守生张淹
Owner SHAN DONG DONG E E JIAO