Continuous gas in-tube solid phase microextraction device combined with gas chromatography for use

Abstract

The invention discloses a continuous gas in-tube solid phase microextraction device combined with gas chromatography (GC) for use. The continuous gas in-tube solid phase microextraction device comprises a continuous gas in-tube solid phase microextraction device and a sampling device, wherein the continuous gas in-tube solid phase microextraction device is composed of an in-tube solid phase microextraction needle, a semiconductor condenser, a microheater and an inert gas connecting pipe, and the sampling device is composed of the in-tube solid phase microextraction needle, and a stop valve, a carrier gas flow controller and a gas source which are connected in sequence through a connector connected with a port of an extraction needle on one end of the in-tube solid phase microextraction needle and are used with the gas chromatography. According to the invention, the extraction needle performs thermal desorption at a GC sample inlet without changing the GC sample inlet and thus the continuous gas in-tube solid phase microextraction device is applied to the GC with any brand. The invention has the advantages of simple operating method, high extraction rate, accurate quantification, hydrophilic environment, convenient automatic operation and the like and also provides a sample pretreatment method integrated with extraction, separation and concentration. The continuous gas in-tube solid phase microextraction device can greatly promote the combination use of the SPME (solid phase microextraction) technology and the GC / MS (mass spectra) technology and applications of micro constituents in complex samples in aspects of on-site analysis, on-line analysis and in-situ analysis.

Description

technical field [0001] The invention relates to a solid-phase microextraction sample pretreatment method and a gas chromatographic device, in particular to a continuous gas in-pipe solid-phase microextraction device combined with the gas chromatograph. Background technique [0002] For the analysis of volatile or semi-volatile micro / trace organic components, solid phase microextraction (SPME) technology and gas chromatography / mass spectrometry (GC / MS) analysis technology are currently the most attractive sample pretreatment techniques and analysis tool. Solid-phase microextraction is a novel sample pretreatment technique proposed and developed by Pawliszyn et al. in 1989, which is fast, sensitive, and convenient for gas and liquid samples. This technology is a new extraction and separation technology developed on the basis of solid phase extraction (SPE). It overcomes almost all the shortcomings of traditional sample processing methods. No need for organic solvents, simpl...

AI Technical Summary

Problems solved by technology

However, there are still some deficiencies in solid-phase microextraction, which need to be further developed and improved, such as poor reliability, inaccurate quantification, and the enrichment factor and selectivity of the extraction still need to be further improved.

The currently used headspace-solid-phase microextraction method has the advantages of extraction, purification, and concentration, but it has not met the requirements of complete enrichment, and this method always gives very low yields for semi-volatile substances. Extraction rate

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