Nucleic acid extraction device capable of preventing cross-contamination

Abstract

The invention discloses a nucleic acid extraction device capable of preventing cross-contamination. The device comprises a motor, a motor control circuit, a stirring sleeve frame which is driven by the motor, stirring sleeves which are arranged on the stirring sleeve frame, and sampling boards, wherein guide grooves are formed on the stirring sleeve frame; each stirring sleeve is provided with a connecting part, and stirring sleeve feet which are formed by extending from the connecting part; the bottom of each stirring sleeve foot has a rotary double-leaf double-curved-surface structure; each stirring sleeve is in clamping fit with the guide grooves of the stirring sleeve frame through curve-shaped guide rails which are arranged on two sides of the connecting part; and the motor control circuit controls the motion of the motor according to input parameters of sample information and further controls the motion track of the stirring sleeves in deep holes of the sampling boards. The nucleic acid extraction device effectively prevents the cross-contamination caused by the mutual influence of aerosol and liquid droplets among samples in the automatic nucleic acid extraction process, and ensures that nucleic acid extraction results are accurate and reliable.

Description

technical field [0001] The invention relates to the technical field of nucleic acid extraction, in particular to a nucleic acid extraction device capable of preventing cross-contamination between sampling holes. , food safety and other life science research and clinical applications. Background technique [0002] Nucleic acid (ribonucleic acid RNA, deoxyribonucleic acid DNA) is the basic unit representing the genetic characteristics of living organisms. Nucleic acid detection is an advanced biological detection at the molecular level. Compared with traditional morphological detection, cytological detection, immunological detection, etc. With more obvious advantages such as sensitivity, specificity, and window-free period, nucleic acid detection has gradually been recognized as a standard gold standard method in recent years, and is widely used in major infectious diseases such as hepatitis and AIDS, as well as SARS, influenza, hand-foot-mouth disease, etc. Detection and dia...

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Problems solved by technology

[0005] The design of the nucleic acid extractor includes automatic mechanisms, controls, and software modules that meet the requirements of nucleic acid extraction, and can extract 32 or 96 biological samples at the same time to achieve the purpose of extracting high work efficiency, which brings a big problem : How to avoid cross-contamination between different samples due to the interaction of aerosols and liquid droplets, that is, how to ensure that any sample to be tested is not polluted and affected by adjacent samples. The nucleic acid extraction process has very strict anti-cross-contamination requirements, so the technical measures and devices to prevent cross-contamination have become a bottleneck in the design technology of nucleic acid extractors

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