Biomechanical property testing method for blood vessel prosthesis and device thereof

A technology of artificial blood vessels and testing devices, which is applied in the field of performance testing of medical biomaterials, and can solve problems such as fatigue characterization and limitations of achievable mechanical testing functions

Inactive Publication Date: 2012-09-19
SUZHOU UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese invention patent (CN101105435B) discloses a textile-type artificial blood vessel fatigue performance bionic test device and its testing method. The sample will undergo fatigue damage under the influence of long-term pulsating liquid. It monitors the density of textile-type artificial blood vessels. However, the samples prepared by other methods are limited in terms of fatigue characterization and achievable mechanical test functions.

Method used

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  • Biomechanical property testing method for blood vessel prosthesis and device thereof
  • Biomechanical property testing method for blood vessel prosthesis and device thereof
  • Biomechanical property testing method for blood vessel prosthesis and device thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] See attached figure 1 , the present embodiment provides the biomechanical performance testing device of the artificial blood vessel, which consists of a liquid storage tank 1, a diversion silicone tube 2, an electronic peristaltic pump 3, a sample fixing device 4, a current limiting switch 5, a pressure testing device 6, and a displacement testing device 7 , wire 8, a computer 9 and a data output device 10 equipped with processing and conversion signals; see attached figure 2 , The sample fixing device 4 is composed of a plexiglass box 41 with holes on the side, a three-way pipe 42, and a two-way pipe 43. The three-way pipe 42 and the two-way pipe 43 are respectively connected together with the plexiglass case 41 through the side holes, and the two ends of the sample S are respectively connected to one end of the three-way pipe 42 and one end of the two-way pipe 43 in the plexiglass case 41 . One of the other two ports of the three-way pipe 42 is connected to the out...

Embodiment 2

[0065] The sample provided in this example is a small-diameter electrospun artificial blood vessel with a diameter of 3 mm and a length of 3 cm, and its biomechanical properties are tested. The specific test steps are as follows:

[0066] (1) Turn on the power supply, turn on the computer 9 and the DC stabilized voltage power supply 62 equipped with processing and conversion signal software, and preheat for twenty minutes to half an hour.

[0067] (2) Add a sufficient amount of liquid into the liquid storage tank 1, wherein the liquid can be water or other liquids that simulate the properties of blood.

[0068] (3) Select the artificial blood vessel sample with a diameter of 3 mm and a length of 3 cm. Select a tee pipe 42 and a two-way pipe 43 with an outer diameter of 3 mm. Put the left end of the sample tightly on the right end of the three-way pipe 42 on the left side of the sample fixing device 4, and then tightly fit the right end of the sample on the left end of the two...

Embodiment 3

[0075] The biomechanical properties of the surface-coated woven polyester artificial blood vessel with a diameter of 10 mm and a length of 8 cm were tested. The specific test steps are as follows:

[0076] (1) Turn on the power supply, turn on the computer 9 and the DC stabilized voltage power supply 62 equipped with processing and conversion signal software, and preheat for twenty minutes to half an hour.

[0077] (2) Add a sufficient amount of liquid into the liquid storage tank 1, wherein the liquid can be water or other liquids that simulate the properties of blood.

[0078] (3) Select the artificial blood vessel sample with a diameter of 10 mm and a length of 8 cm. Select a tee pipe 42 and a two-way pipe 43 with an outer diameter of 10 mm. Put the left end of the sample tightly on the right end of the three-way pipe 42 on the left side of the sample fixing device 4, and then tightly fit the right end of the sample on the left end of the two-way pipe 43 on the right side ...

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Abstract

The invention belongs to the technical field of medical biomaterial property test, and particularly relates to a biomechanical property testing device and a testing method for blood vessel prosthesis. The testing device includes a liquid storage box, a current guide silicon tube, an electronic peristaltic pump, a current limit switch, a conducting wire, a computer mounted with signal processing and converting software and data output equipment as well as a sample fixing device, a pressure testing device and a displacement testing device. By utilizing the device, the relation curve of the pressure and the tube diameter is measured and recorded in real time, so that the detecting results of compliance, fatigue resistance and bursting pressure are calculated and obtained, and the biomechanical properties of the blood vessel prosthesis are scientifically tested and evaluated; therefore, the technical problem of testing the biomechanical properties of the integral blood vessel prosthesis under the existing physiological status is solved, the integral testing and evaluation of the compliance, the fatigue resistance and the bursting pressure of the blood vessel prosthesis are realized, and scientific and reliable evidences are provided for choosing the blood vessel prosthesis with the biomechanical properties meeting the requirements.

Description

technical field [0001] The invention relates to a device for testing biomechanical properties of artificial blood vessels and a testing method thereof, belonging to the technical field of testing medical biomaterial properties. Background technique [0002] After the artificial blood vessel is implanted in the living body, it will be in a variety of complex vascular physiological environments, not only bearing periodic pressure and stretching force (circumferential stress) perpendicular to the direction of blood flow, but also with the flow of blood, the artificial blood vessel also bears The frictional force (shear stress) parallel to the direction of blood flow, therefore, the artificial blood vessel is required to have the structural strength, elastic-plasticity and stability when supporting expansion, contraction and friction; in addition, the artificial blood vessel has a long service life in the body. For degradable artificial vascular stents, its degradation rate in t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N3/12
Inventor 赵荟菁吕强王璐
Owner SUZHOU UNIV
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