Chinese traditional medicine capsule for treating lupus erythematosus and preparation method thereof

A technology of traditional Chinese medicine capsules and lupus erythematosus is applied in the directions of capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. The effect of convenience, good efficacy and quality control

Inactive Publication Date: 2012-09-26
ZHONGSHAN HOSPITAL FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a traditional Chinese medicine capsule for the treatment of lupus erythematosus and its preparation method, which can overcome the

Method used

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  • Chinese traditional medicine capsule for treating lupus erythematosus and preparation method thereof
  • Chinese traditional medicine capsule for treating lupus erythematosus and preparation method thereof
  • Chinese traditional medicine capsule for treating lupus erythematosus and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1: Chinese medicine capsule for the treatment of lupus erythematosus and preparation method thereof

[0042] Get each 32 kilograms (96 kilograms) of tripterygium wilfordii (totally 96 kilograms) of identified Red Teng, Spatholobus Spatholobus and peeled root, put into 1 ton of extraction tank and mix, add 6 times of weight of 90vol% ethanol (576 kilograms), reflux Extract for 2 hours, filter the extract, recover ethanol from the filtrate, and concentrate to a relative density of 1.287g / cm 3 , 5.98 kg of Santeng liquid extract was obtained.

[0043] Add 1.3 kg of dextrin, mix, dry at 80°C, and powder to obtain 5.32 kg of Santeng dry powder, which is packed into No. 0 capsules, 0.44 g per capsule, and 12060 Santeng capsules are prepared in total, 45 capsules / bottle. Put in a dry bag and seal. (4.02 kg of dry extract, yield 4.18%).

Embodiment 2

[0044] Embodiment 2: Chinese medicine capsule for the treatment of lupus erythematosus and preparation method thereof

[0045] Get each 32 kilograms (96 kilograms) of tripterygium wilfordii (totally 96 kilograms) of identified Red Teng, Spatholobus Spatholobus and peeled root, put into 1 ton of extraction tank and mix, add 6 times of weight of 90vol% ethanol (576 kilograms), reflux Extract for 2 hours, filter the extract, recover ethanol from the filtrate, and concentrate to a relative density of 1.293g / cm 3 , 6.09 kg of Santeng liquid extract was obtained.

[0046] Add 1.3 kg of dextrin, mix, dry at 80°C, and powder to obtain 5.39 kg of Santeng dry powder, which is packed into No. 0 capsules, 0.44 g per capsule, and 12,210 Santeng capsules are prepared in total, 45 capsules / bottle. Put in a dry bag and seal.

Embodiment 3

[0047] Embodiment 3: Chinese medicine capsule for the treatment of lupus erythematosus and preparation method thereof

[0048] Get each 32 kilograms (96 kilograms) of tripterygium wilfordii (totally 96 kilograms) of identified Red Teng, Spatholobus Spatholobus and peeled root, put into 1 ton of extraction tank and mix, add 6 times of weight of 90vol% ethanol (576 kilograms), reflux Extract for 2 hours, filter the extract, recover ethanol from the filtrate, and concentrate to a relative density of 1.281g / cm 3 , 5.91 kg of Santeng liquid extract was obtained.

[0049] Add 1.3 kg of dextrin, mix, dry at 80°C, and powder to obtain 5.25 kg of Santeng dry powder, which is packed into No. 0 capsules, 0.44 g per capsule, and 11,910 Santeng capsules are prepared in total, 45 capsules / bottle. Put in a dry bag and seal.

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Abstract

The invention discloses a Chinese traditional medicine capsule for treating lupus erythematosus and a preparation method of the Chinese traditional medicine capsule. The Chinese traditional medicine capsule for treating lupus erythematosus is characterized in that the raw materials comprise 15-45 parts by weight of peeled thunder god vine with removed roots, 15-45 parts by weight of leatherleaf milletia and 15-45 parts by weight of sargentgloryvine stem. The invention also provides a preparation method of the Chinese traditional medicine capsule for treating lupus erythematosus. According to the invention, the effective ingredients of the three raw material medicines can be effectively extracted, and the prepared capsule has a better effect than the original three-rattan mixture; and the quality can be effectively controlled, the capsule is convenient to take and carry, and the storage time is longer.

Description

technical field [0001] The invention relates to a traditional Chinese medicine capsule for treating lupus erythematosus and a preparation method thereof, belonging to the technical field of compound traditional Chinese medicine preparations. Background technique [0002] Systemic lupus erythematosus (SLE) is an autoimmune disease that invades multiple systems and seriously endangers human health. One of the most commonly affected organs. According to the relevant statistics of renal biopsy, the renal involvement rate of SLE patients is almost 100%, manifested as proteinuria, hematuria, and casturia. Lupus nephritis (lupus nephritis, LN) is the most common secondary renal disease, and the end-stage renal disease (ESRD) caused by it is the main cause of death in SLE patients. At present, according to the 2011 report of the Chinese Systemic Lupus Erythematosus Research Collaboration Group (CSTAR), the global average prevalence rate is 12-39 / 100,000, and the prevalence rate of...

Claims

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Application Information

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IPC IPC(8): A61K36/486A61K9/48A61P37/02
Inventor 秦万章杨春欣王强沈熊
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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