Enrofloxacin injection for livestock and preparation method thereof

A technology of enrofloxacin and injection, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, organic active ingredients, etc., can solve the problems of increased drug residues, production crystallization, limited solubility, etc., and achieve less adverse reactions , good frost resistance, strong efficacy
CN102697784BActive Publication Date: 2014-06-25武汉回盛生物科技股份有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
武汉回盛生物科技股份有限公司
Publication Date
2014-06-25

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Abstract

The invention relates to the technical field of a pharmaceutical preparation for livestock and specifically discloses an enrofloxacin injection for the livestock and a preparation method thereof. The raw material of the injection is composed of enrofloxacin, artesunate, trimethoprim, flunixin meglumine, L-arginine, antioxidant, chelant, compound organic solvent and water for injection. The enrofloxacin injection for the livestock can effectively enhance the antibacterial effect of the drug, has an excellent anti-inflammatory effect and is mainly used for treating serious mixed infection caused by sensitive bacteria and mycoplasma of the livestock; the generation of drug resistance is effectively reduced; and the toxic and side effects are reduced. The preparation method for the enrofloxacin injection for the livestock provided by the invention is simple, low-cost, high in stability, convenient in use, and suitable for industrial production.
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Description

technical field

[0001] The invention relates to the technical field of veterinary pharmaceutical preparations, in particular to a veterinary enrofloxacin injection and a preparation method of the injection. Background technique

[0002] Enrofloxacin is a third-generation fluoroquinolone broad-spectrum antibacterial drug specially used for animals. It has a broad-spectrum bactericidal effect and can kill Gram-negative bacilli, cocci, positive bacteria, mycoplasma, and chlamydia. It is effective for both quiescent and growing bacteria. Sensitive bacteria die within 20-30 minutes after contact with this product. It has strong bactericidal activity, high efficiency and low toxicity. It is mainly used clinically to treat enteritis, pneumonia, mastitis and soft tissue infectious diseases caused by livestock and poultry bacteria and mycoplasma.

[0003] Meinen et al. (1995) showed that the bactericidal effect of enrofloxacin is concentration-dependent. In tissues and plasma, the ...

Claims

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