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Compound polyethylene glycol electrolyte composition

A technology of polyethylene glycol and composition, which is applied in the field of medicine and can solve problems such as patient resistance and bad taste of the solution

Active Publication Date: 2012-11-14
SHENZHEN WANHE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] As with other laxatives and bowel cleansing compositions, many patients are taking Movicol or polyethylene glycol-based compositions to treat stagnant stools, the solution tastes bad
These adverse feelings can lead to the patient's resistance

Method used

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  • Compound polyethylene glycol electrolyte composition
  • Compound polyethylene glycol electrolyte composition
  • Compound polyethylene glycol electrolyte composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Embodiment 1: preparation composition of the present invention

[0108] Formula (prepared on the basis of 10kg of total material per batch):

[0109] Polyethylene glycol (Mr=3050, HV=55)

[0110] Preparation method: crush polyethylene glycol and pass through a 50-mesh sieve, and crush the rest of the materials separately and pass through a 65-mesh sieve, and dry at 40-45°C for 2 hours; mix sodium chloride, potassium chloride, sodium bicarbonate, The anhydrous sodium sulfate is uniformly mixed to obtain an electrolyte mixture; and then the electrolyte mixture and polyethylene glycol are substantially uniformly mixed by an equal-volume increasing method to obtain the composition of the present invention and packaged.

Embodiment 2

[0111] Embodiment 2: preparation composition of the present invention

[0112] Formula (prepared on the basis of 10kg of total material per batch):

[0113] Polyethylene glycol (Mr=2800, HV=59)

[0114] Preparation method: with embodiment 1.

Embodiment 3

[0115] Embodiment 3: preparation composition of the present invention

[0116] Formula (prepared on the basis of 10kg of total material per batch):

[0117] Polyethylene glycol (Mr=3100, HV=53)

[0118] Preparation method: Mix the crushed and passed 80 mesh sodium chloride, potassium chloride, sodium bicarbonate, and anhydrous sodium sulfate to obtain the inorganic salt raw material mixture, and then mix the inorganic salt raw material mixture with the crushed and passed 65 mesh polyethylene glycol The PEG is fed separately by two feeding hoppers, and packed into a packaging bag.

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PUM

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Abstract

The invention relates to a compound polyethylene glycol electrolyte composition, and in particular relates to a composition containing polyethylene glycol and electrolyte. The composition comprises the following components: polyethylene glycol, potassium chloride, sodium bicarbonate and anhydrous sodium sulfate. According to 6000 parts of polyethylene glycol, the composition comprises 118-178 parts of sodium chloride, 60-90 parts of potassium chloride, 137-205 parts of sodium bicarbonate and 461-692 parts of anhydrous sodium sulfate. The composition disclosed by the invention has good pharmaceutical properties.

Description

technical field [0001] The invention relates to the field of medicine, and relates to a composition containing polyethylene glycol and electrolytes and a preparation method thereof, in particular to a compound polyethylene glycol electrolyte powder and a preparation method thereof. The composition of the present invention can be used for treating constipation, fecal obstruction, fecal stagnation, gas spasm, flatulence, and can also be used for standing enema, colon purgative or colon cleansing. Background technique [0002] Constipation is a common condition that often causes discomfort. Stool retention in the colon and / or rectum can cause discomfort and headaches. In extreme cases, the presence of hard or dry stools in the rectum can cause prolonged constipation and painful stools. [0003] Many treatments for constipation have been developed, including dietary controls (eg, increasing the fiber content of foods and avoiding foods thought to cause constipation), laxatives...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61K9/14A61P3/12A61P1/10A61P1/06A61P1/14G01N31/16A61K31/765A61K33/04A61K33/00
Inventor 衷期群马双飞刘晓燕
Owner SHENZHEN WANHE PHARMA
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