Protein derived from Trichoderma reesei and gene application thereof

A technology of Trichoderma reesei and genes, applied in the direction of microorganism-based methods, using vectors to introduce foreign genetic material, cells modified by introducing foreign genetic material, etc., can solve the problem of regulatory factors not being discovered
CN102787108AInactive Publication Date: 2012-11-21INST OF MICROBIOLOGY - CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF MICROBIOLOGY - CHINESE ACAD OF SCI
Publication Date
2012-11-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a protein derived from Trichoderma reesei and application the gene of the protein. The application is the application of the Trfogl to controlling the extracellular protein secretion amount of the Trichoderma reesei, and the Trfogl is the protein shown by an amino acid sequence such as a sequence 2 in a sequence table. According to the invention, a technical base is provided for constructing Trichoderma reesei host bacteria and engineering bacteria with an increased extracellular protein secretion amount.
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Description

technical field

[0001] The present invention relates to the use of a protein derived from Trichoderma reesei and its gene, in particular to the application of Trfog1 derived from Trichoderma reesei in regulating the secretion of extracellular protein of Trichoderma reesei. Background technique

[0002] The filamentous fungus Trichoderma reesei (Trichoderma reesei) is a mesophilic saprophytic fungus, which is widely used in the production of cellulose and hemicellulase for food, feed, textile, pulp and paper industries. At present, it has become an important model strain for the study of cellulose degradation. Trichoderma reesei is an FDA-certified safe production strain with strong protein secretion ability and a glycosylation system similar to higher mammals, so Trichoderma reesei is also an ideal host for recombinant protein expression. In order to further increase the production of cellulase hemicellulase of Trichoderma reesei and at the same time increase the secretion ...

Claims

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