Traditional Chinese medicine composite containing angelica sinensis and having function of treating endometriosis

Abstract

The invention belongs to the field of combination with the traditional Chinese medicine, obstetrics and gynecology and molecular pharmacology, and particularly relates to a traditional Chinese medicine composite containing angelica sinensis and having the function of treating endometriosis. The traditional Chinese medicine composite can restrain the expression level of the apoptosis inhibition factors Bc1-2 and Survivin in the endometriotic tissues of the endometriosis, and can promote the expression level of the apoptosis promoting factor Bax. The composite comprises the active ingredients in parts by weight: 1200 parts of angelica sinensis, 1000 parts of Chinese herbaceous peony, 1000 parts of cassia twig and 1000 parts of poria cocos. In the prescription, the angelica sinensis is warm in nature, and sweet and acrid in taste, can invigorate the circulation of blood, and has the function of removing stasis without disordering blood, thereby the angelica sinensis is a monarch medicament; the Chinese herbaceous peony is bitter in taste and bit in cold, not only can remove stasis by invigorating the circulation of blood, but also can remove stasis and durably dissipate hot by cooling the blood, thus the Chinese herbaceous peony is a ministerial medicament; the cassia twig is sweet, acrid and warm, and has the functions of warming blood vessel in which the blood and qi circulate, mediating Yin, activating Yang, and removing stasis; and the poria cocos is sweet and tasteless, and has the function of inducing diuresis with bland drug, thus the poria cocos is an adjuvant with the cassia twig to be good for removing defects. Various medicaments are jointly used, so that the traditional Chinese medicine composite has the functions of warming channel and dredging veins, removing stasis and generating freshness, and removing stasis and removing defects.

Description

technical field [0001] The invention belongs to the field of combining traditional Chinese medicine, obstetrics and gynecology, and molecular pharmacology, and specifically relates to a Chinese medicine composition containing angelica, which can inhibit apoptosis in endometriosis ectopic endometrium tissue The expression levels of factors Bcl-2 and Survivin can be inhibited, and the expression levels of apoptosis-promoting factor Bax can be promoted, so that endometriosis can be treated through this special mechanism. Background technique [0002] Endometriosis (endometriosis, EMs) is a common benign hormone-dependent disease, the incidence rate of women of childbearing age is as high as 10% to 15%, accounting for more than 30% of general gynecological surgery. And there is a trend of gradual increase, which is the main cause of women's dysmenorrhea, infertility, and chronic pelvic pain clinically, and the drug treatment and postoperative recurrence rate are relatively high....

AI Technical Summary

Problems solved by technology

And there is a trend of gradual increase, which is the main cause of women's dysmenorrhea, infertility, and chronic pelvic pain clinically, and the drug treatment and postoperative recurrence rate are high

Images