Traditional Chinese medicine composition for treating constipation, preparation method and application

A technology for treating constipation and a composition is applied in the field of traditional Chinese medicine compositions and preparations for treating constipation, which can solve the problems of treating the symptoms but not the root cause, unstable curative effect, low cure rate and the like, and achieves the effects of no toxic and side effects, strict compatibility and definite curative effect.

Active Publication Date: 2013-02-27
海门江海建设投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine uses "Dachengqi Decoction", rhubarb, senna, magnesium sulfate, etc. to laxative stools, which are still dry and hard after relapse; "Kaisaitong" relieves the disease, but it has the disadvantages of treating the symptoms but not the root cause, the curative effect is unstable, the cure rate is low, generally 20%, and it is easy to relapse

Method used

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  • Traditional Chinese medicine composition for treating constipation, preparation method and application
  • Traditional Chinese medicine composition for treating constipation, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: Take 18g of Huoxiang, 65g of Magnolia officinalis, 18g of Radix Paeoniae Alba, 12g of Peony, 8g of Platycodon grandiflorum, 17g of almonds, 10g of Trichosanthes seeds, 14g of angelica, and 18g of peach kernels. The amount is 10 times the weight of the medicinal material, decocted for 1.5 hours, and the second time adding water is 8 times the weight of the medicinal material, decocted for 1.5 hours, combined the decoction, concentrated under reduced pressure at 0.07MPa, 60-70 °C to 65 °C For the extract with a density of 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure at 0.07MPa and 65°C The relative density is 1.25 when it reaches 65°C, and the ethanol is recovered to obtain a concentrated solution, which is spray-dried (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 85°C, the material temperature is 80°C, an...

Embodiment 2

[0026] Example 2: Take Huoxiang 20g, Magnolia officinalis 60g, Paeoniae Alba 20g, Peony 10g, Bellflower 10g, Almond 15g, Trichosanthes 12g, Angelica 12g, peach kernel 20g medicinal materials, add water to decoct twice, add water for the first time 8 times the weight of the medicinal material, decocted for 1 hour, added water for the second time to 6 times the weight of the medicinal material, decocted for 1 hour, combined the decoction, concentrated under reduced pressure at 0.07MPa, 60-70 °C to 65 °C, and the relative density was 1.20, add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stir, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure at 0.07MPa and 65°C to 65°C The relative density is 1.30, and the ethanol is recovered to obtain a concentrated solution, which is filtered, added with water and sucrose to prepare an oral solution.

Embodiment 3

[0027] Example 3: Take 22g of Huoxiang, 55g of Magnolia officinalis, 22g of Radix Paeoniae Alba, 8g of Peony, 12g of Platycodon grandiflorum, 13g of almonds, 14g of Trichosanthes seeds, 10g of angelica, and 22g of peach kernels, add water to decoct twice, add water for the first time 12 times the weight of the medicinal material, decocted for 2 hours, added water for the second time to 10 times the weight of the medicinal material, decocted for 2 hours, combined the decoction, concentrated under reduced pressure at 0.07MPa, 60-70°C to 65°C, and the relative density was 1.20 extract, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure at 0.07MPa and 65°C to The relative density is 1.30 at 65°C, and the ethanol is recovered to obtain a concentrated solution, which is spray-dried (conditions are that the inlet air temperature is 120°C, the outlet air temperature is 90°C, the ma...

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Abstract

The invention provides a traditional Chinese medicine composition for treating constipation, a preparation method and an application. The traditional Chinese medicine composition is mainly composed of the following components in parts by weight:18-22 parts of ageratum, 55-65 parts of cortex magnoliae officinalis, 18-22 parts of paeonia lactiflora pallas, 8-12 parts of delavay soapberry pericarp seed, 8-12 parts of dried old orange peel, 13-17 parts of almond, 10-14 parts of semen trichosanthis, 10-14 parts of angelica and 18-22 parts of peach kernels, and the composition is prepared to oral liquid, tablets, capsules or granules by a corresponding preparation method. The traditional Chinese medicine composition has the functions of tonifying middle-Jiao and Qi and invigorating and activating spleen, and the traditional Chinese medicine composition is used for treating constipation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating constipation, a preparation method and application thereof. Background technique [0002] Constipation is a common clinical symptom rather than a disease. It mainly refers to decreased frequency of defecation, decreased amount of feces, dry feces, and laborious defecation. When two or more of the above symptoms are present at the same time, it can be diagnosed as symptomatic constipation. Usually, the main reason is a decrease in the frequency of defecation. Generally, one defecation every 2 to 3 days or longer (or <3 times per week) is constipation. The results of a survey of a group of healthy people show that the habit of defecation is mostly 1-2 times a day or once a day (60%), and the stools are mostly shaped or soft; a small number of healthy people can defecate up to 3 times a day Once (30%)...

Claims

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Application Information

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IPC IPC(8): A61K36/77A61P1/10
Inventor 不公告发明人
Owner 海门江海建设投资有限公司
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