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Manufacturing method of ceramide and/or glucose ceramide production promoter

A kind of ceramide, the technology of the manufacturing method, is applied in the field of ceramide and/or glucosylceramide production accelerator, achieves the effect of improving moisturizing ability

Inactive Publication Date: 2013-03-27
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, there is no report on the use of microorganisms of the genus Geotrichum to produce ceramide and / or glucosylceramide production accelerators

Method used

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  • Manufacturing method of ceramide and/or glucose ceramide production promoter

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] (Manufacture of ceramide and / or glucosylceramide production promoter)

[0051] As a microorganism for producing ceramide and / or glucosylceramide production accelerator from bean dregs, use fermentative Geotrichum fermentans (purchased from Jiangnan University, and preserved in CICIM, China Universities Industrial Microbial Resources and Information Center, deposit number CICIM Y0256).

[0052] Inoculate the above strain obtained by culturing in YPD (Yeast Extract Peptone Dextrose Medium) medium at 30°C into a Erlenmeyer flask (capacity 300ml) containing 100ml of ceramide / glucosylceramide production promoter production medium, and inoculate at 30°C cultured for 72 hours. The medium contained 10 w / v% okara and 1 w / v% glucose. Wherein, the preparation of soybean dregs is obtained by soaking soybeans in water for 12 hours to make soybeans fully absorb water, then grinding and crushing the soybeans that have absorbed water, filtering and removing liquid components, and dra...

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Abstract

The invention provides a manufacturing method of a ceramide and / or glucose ceramide production promoter, wherein the ceramide and / or glucose ceramide production promoter is obtained from supernatant fluid of a microorganism of Geotrichum, which is cultured in a culture medium containing bean dregs and saccharides. According to the manufacturing method disclosed by the invention, the specific microorganism can be utilized, and a byproduct, namely the bean dregs in the food processing industry and the like can be used as a main raw material of the culture medium, so that the ceramide and / or glucose ceramide production promoter can be obtained with low cost and high efficiency.

Description

Technical field [0001] The present invention relates to a method for producing a ceramide and / or glucosylceramide production accelerator that can promote the production of ceramide and / or glucosylceramide in the skin by using specific microorganisms and using bean dregs, a by-product of the food processing industry, as the main raw material of the culture medium. . Background technique [0002] Ceramide, one of the sphingolipids, is present in the stratum corneum of the skin and accounts for about 50% of the intercellular lipids in the stratum corneum. Sphingolipid is a general term for complex lipids with a sphingosine skeleton. Glucosylceramide is a sphingolipid formed by combining glucose with ceramide. Ceramide synthesized by epidermal cells is temporarily stored in the form of glucosylceramide or sphingomyelin; it is then excreted out of the cell where it is processed by glucocerebrosidase and sphingomyelinase. Under the action of , it becomes ceramide again, thereby...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P1/02A61K8/99A61Q19/00C12R1/645
Inventor 孔凡旗
Owner KAO CORP