The invention discloses hand cream which comprises water, ethanol, propylene glycol, butanediol, isopropyl palmitate, cetostearyl alcohol, hyaluronic acid, Carbomer, milk protein, tocopherol, allantoin, hydroxyethyl cellulose, DMDM hydantoin, PEG-7 glyceryl cocoate, PEG-40 hydrogenated castor oil, polysorbate-20, phenoxyethanol, chlorphenesin, glycerin, sodium polyacrylate, sodium benzoate, menthol PCA ester, bio-saccharide gum 1, evening primrose seed oil, avocado oil, olive-pomace oil, Blumea oil, spearmint leaf oil, ginseng extract, catnip leaf extract, pearl extract, herba centellae, immortelle extract, oryza sativa oil, grape seed extract, aloe extract, tremella extract, propolis, donkey-hide gelatin, saffron crocus extract, rhodiola rosea extract, radix angelicae extract, tea extract, lemon juice, rose extract, alcohol extract of verbena officinalis, lavender extract and salvia officinalis extract. The hand cream disclosed by the invention can achieve a good effect of moistening hand skin.