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Method for preparing lauric acid monoglyceride by immobilized lipase

A technology of monolauric acid monoglycerol and immobilized lipase, which is applied in the field of preparation of monolauric acid monoglyceride, can solve the problems of large acid-base salt discharge, non-recyclable, harsh reaction conditions, etc., and achieve resource and cost saving, The effect of low cost and mild reaction conditions

Inactive Publication Date: 2013-05-01
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this type of process has the following disadvantages: the catalyst used is liquid or solid acid-base, which cannot be reused; the discharge of acid-base salt is large, which is harmful to the environment; usually high temperature and high pressure process is required, the reaction conditions are harsh, the operation is cumbersome, and the investment in equipment is large. , high production cost

Method used

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  • Method for preparing lauric acid monoglyceride by immobilized lipase
  • Method for preparing lauric acid monoglyceride by immobilized lipase

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] (1) transesterification

[0025] Add 55.7 grams of coconut oil and 29.1 grams of glycerin into a 150mL flat-bottomed flask (the molar ratio of the two is 1:3, and the water content of glycerin is 4%). After the temperature (50°C), add 4.456g Novozym 435 immobilized lipase (Novozymes) (the amount added is 8% of the weight of the above coconut oil), stir constantly, and continue to place it in the above constant temperature water bath for transesterification Reaction, time 36h.

[0026] (2) centrifugal

[0027] The transesterification product obtained in step (1) is placed in a centrifuge with a centrifugal force of 5000g to separate the immobilized lipase and unreacted glycerin, and the upper oil phase is taken as a mixture of fatty acid glycerides.

[0028] (3) Primary molecular distillation

[0029] The fatty acid glyceride mixture obtained in step (2) is subjected to primary molecular distillation using a scraped-film short-range molecular distillation apparatus (p...

Embodiment 2

[0033] (1) transesterification

[0034] Add 55.7 grams of coconut oil and 38.8 grams of glycerin into a 150mL flat-bottomed flask (the molar ratio of the two is 1:4, and the water content of glycerin is 5%). After the temperature (40°C), add 3.342g Lipozyme TL IM immobilized lipase (same as above) (the amount added is 6% of the weight of the above coconut oil), stir constantly, and continue to place it in the above constant temperature water bath for the transesterification reaction. Time 24h.

[0035] (2) centrifugal

[0036] The transesterification product obtained in step (1) is placed in a centrifuge with a centrifugal force of 5500g to separate the immobilized lipase and unreacted glycerin, and the upper oil phase is taken as a mixture of fatty acid glycerides.

[0037] (3) Primary molecular distillation

[0038] The fatty acid glyceride mixture obtained in step (2) is subjected to primary molecular distillation using a wiped-film short-range molecular distillation app...

Embodiment 3

[0042] (1) transesterification

[0043] Add 55.7 grams of coconut oil and 38.8 grams of glycerin into a 150mL flat-bottomed flask (the molar ratio of the two is 1:4, and the water content of glycerin is 5%). After the temperature (40°C), add 2.785g Lipozyme RM IM immobilized lipase (same as above) (the amount added is 5% of the weight of the above coconut oil), stir constantly, and continue to place it in the above constant temperature water bath for the transesterification reaction. Time 48h.

[0044] (2) centrifugal

[0045] The transesterification product obtained in step (1) is placed in a centrifuge with a centrifugal force of 5000g to separate the immobilized lipase and unreacted glycerin, and the upper oil phase is taken as a mixture of fatty acid glycerides.

[0046] (3) Primary molecular distillation

[0047]The fatty acid glyceride mixture obtained in step (2) is subjected to primary molecular distillation using a wiped-film short-range molecular distillation appa...

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Abstract

The invention discloses a method for preparing lauric acid monoglyceride by immobilized lipase. The method comprises the processing steps as follows: (1), ester exchange: mixing a defined amount of coconut oil with glycerol, heating to a preset temperature, and taking immobilized lipase as a catalyst to perform an ester exchange reaction; (2), centrifugation: after the ester change reaction, subjecting a mixture to the centrifugation to form an upper layer oil phase, namely a fatty glyceride mixture; and (3), molecular distillation: molecularly distilling the mixture of the glyceride under certain conditions, obtaining distilled residues through first-level molecular distillation, performing second-level molecular distillation for the distilled residues, and distilling out a light phase, namely the finished product of immobilized lipase. The method for preparing lauric acid monoglyceride by immobilized lipase has the advantages of mild reaction conditions, simple operation, convenience in operation, high production efficiency, low cost and no harm to the environment; and moreover, the catalyst has strong specificity and can be used repeatedly, and accordingly lauric acid monoglyceride with higher purity can be prepared.

Description

technical field [0001] The invention relates to a method for preparing monoglyceride laurate, in particular to a method for preparing monoglyceride laurate by using immobilized lipase to catalyze the transesterification of coconut oil and glycerin, and belongs to the technical field of surfactant synthesis. Background technique [0002] Coconut is a monocotyledon perennial evergreen tree of the palm family, and is a typical tropical woody oil crop. About 87% of coconut plantations are located in member countries of the Asia-Pacific Coconut Community (APCC). Among them, the planting areas of Indonesia and the Philippines account for 23.4% and 27.5% of the world's total respectively. In my country, coconuts are mainly produced in the southeast coast of Hainan Province. Coconut oil is the oil extracted from coconut endosperm after crushing and steaming. It is recognized as a vegetable oil with multiple physiological functions in the world. It can not only promote the absorption...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C11C3/06C11C3/10
Inventor 陈正行郑联合查宝萍王莉王韧王涛
Owner JIANGNAN UNIV
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