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Traditional Chinese medicine preparation for treating dry eye diseases

A traditional Chinese medicine preparation, dry eye technology, applied in the directions of medical preparations, drug combinations, pharmaceutical formulas, etc. containing active ingredients, can solve the problems of dry eye patients with little effect, increase the pain of patients, and the effect is not ideal, and achieve convenient material acquisition Economical, improve curative effect, increase tear secretion effect

Inactive Publication Date: 2013-05-22
THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Dry eye can’t be cured at present, and most of the clinical symptoms are relieved by artificial tears, but if it is more than 6 times a day, the normal tear film will be washed away, which will aggravate the symptoms. Tears have little effect on severe dry eye patients
For severe patients, punctal embolization, autologous submandibular gland transplantation and other surgical treatments can be used. Punctal embolization can relieve symptoms and reduce the amount of artificial tears, and improve the symptoms and signs of patients. For patients with severe dry eye, it may It takes a long time to improve, and the cost is expensive, which increases the suffering of patients and is difficult for ordinary patients to accept
In recent years, there are also many traditional Chinese medicine preparations for the treatment of dry eye, especially the moisturizing eye spirit made of licorice, wolfberry, chrysanthemum, scrophulariaceae, cassia seed, and ghost needle grass, which has achieved certain curative effects in the treatment of dry eye, but the effect still not ideal

Method used

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  • Traditional Chinese medicine preparation for treating dry eye diseases
  • Traditional Chinese medicine preparation for treating dry eye diseases
  • Traditional Chinese medicine preparation for treating dry eye diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1~19

[0036] According to the weight ratio listed in Table 3, according to the conventional preparation method in pharmacy, the granules were obtained in Examples 1-4, the tablets were obtained in Examples 5-9, and the pills were obtained in Examples 10-13. 14~16 makes powder, and embodiment 17~19 makes capsule.

[0037] The weight unit of each raw material in the table of Table 3: kilogram

[0038]

Embodiment 20

[0040] Patient Li Feng, female, 34 years old, has been engaged in computer work for a long time, more than 8 hours a day, according to the diagnostic criteria of dry eye, excluding other systemic diseases, diagnosed as dry eye (left side).

[0041] After taking the tablet prepared in Example 5 of the present invention for a course of treatment (8 weeks), all symptoms and signs disappeared substantially, and the results before and after treatment were shown in the following table 4:

[0042] Table 4

[0043]

Embodiment 21

[0045] Patient Wu Qinghong, male, 45 years old, according to the diagnostic criteria of dry eye, excluding other systemic diseases, was diagnosed as bilateral dry eye, the patient could not work and live normally before treatment, dryness, pain, unbearable seizures, temper tantrum Becoming irritable and almost collapsed; taking the powder prepared by the embodiment of the present invention 14 orally, the symptoms were obviously relieved after a course of treatment (8 weeks), although dry symptoms were often present, they could be relieved and tolerated by rest, without affecting general life and mood.

[0046] The results before and after treatment are shown in Table 5 below:

[0047] table 5

[0048]

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating dry eye diseases, which is prepared from the following raw materials in parts by weight: 6-10 parts of liquorice, 25-35 parts of Chinese wolfberry, 10-20 parts of chrysanthemum, 10-20 parts of radix scrophulariae, 8-15 parts of cassia seeds, 10-30 parts of prepared rhizome of rehmannia, 25-35 parts of radix ophiopogonis, 25-35 parts of astragalus membranaceus, and 25-35 parts of bidens pilosa. The traditional Chinese medicine preparation for treating dry eye diseases can be prepared into any dosage forms by using a pharmaceutically conventional preparation method. The raw materials used in the invention are all pure natural Chinese herbal medicines, therefore, the material taking is convenient and economic, and the preparation method is simple; the curative effect can be improved, especially, and the lacrimal secretion can be increased, thereby relieving the subjective symptoms of patients, and easing the pain; and no toxic or side effect is caused after the preparation is taken for a long time.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating dry eye. Background technique [0002] Dry eye refers to the general term for various diseases caused by abnormal tear quality or quantity or dynamics caused by any reason, resulting in decreased tear film stability, accompanied by ocular discomfort and / or ocular surface tissue lesions. a chronic disease. The survey confirmed that 90% of people who work in front of the computer for more than 3 hours a day suffer from dry eye in varying degrees, and in the next 5 years, the number of dry eye patients will increase at a rate of more than 10% per year. Common symptoms include dry eyes, easy fatigue, drowsiness, itching, foreign body sensation, burning sensation, tight and heavy eyelids, thick secretions, fear of wind, photophobia, sensitivity to external stimuli, and temporary blurred vision; Sometimes the eyes ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P27/02
Inventor 屈健宁
Owner THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIV
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