Composition containing chloroquine phosphate

A technology of chloroquine phosphate and composition, which is applied in the field of chloroquine phosphate composition, and can solve problems such as corruption or decomposition, inaccuracy, and moldy agents

Inactive Publication Date: 2013-07-10
天津市嘉凡生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Biologically, due to the growth of microorganisms, the agent is moldy, corrupted or decomposed
This kind of situation is more common; ③ the patient does not use the same, such as the drug in the suspension precipitates into a hard cake, which is not only inc

Method used

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  • Composition containing chloroquine phosphate

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] prescription:

[0024] Chloroquine Phosphate, 10g

[0025] Sodium histidine, 10g

[0026] Xylitol, 15g

[0027] Alkyltrimethylammonium bromide, 40g

[0028] Sodium Caprylate, 15g

[0029] Process:

[0030] Add the above-mentioned components according to the prescription amount, and mix the chloroquine phosphate, sodium histidine, xylitol, alkyltrimethylammonium bromide and sodium caprylate evenly.

Embodiment 2

[0032] prescription:

[0033] Chloroquine Phosphate, 10g

[0034] Sodium histidine, 5g

[0035] Xylitol, 10g

[0036] Alkyltrimethylammonium bromide, 30g

[0037] Sodium Caprylate, 10g

[0038] Process:

[0039] Add the above-mentioned components according to the prescription amount, and mix the chloroquine phosphate, sodium histidine, xylitol, alkyltrimethylammonium bromide and sodium caprylate evenly.

Embodiment 3

[0041] prescription:

[0042] Chloroquine Phosphate, 10g

[0043] Sodium histidine, 20g

[0044] Xylitol, 20g

[0045] Alkyltrimethylammonium bromide, 50g

[0046] Sodium Caprylate, 20g

[0047] Process:

[0048] Add the above-mentioned components according to the prescription amount, and mix the chloroquine phosphate, sodium histidine, xylitol, alkyltrimethylammonium bromide and sodium caprylate evenly.

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PUM

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Abstract

The invention discloses a composition containing chloroquine phosphate. The composition also contains the following components: 5-20wt% of histidine sodium, 10-20wt% of xylitol, 30-50wt% of alkyl trimethyl ammonium bromide and 10-20wt% of sodium caprylate. The composition has the beneficial effect of good stability.

Description

technical field [0001] The present invention relates to a chloroquine phosphate composition, in particular to a chloroquine phosphate composition, which also contains the following components: 5% to 20% by weight of sodium histidine; 10% to 20% by weight of xylitol; 30 % to 50% by weight of alkyltrimethylammonium bromide; and 10% to 20% by weight of sodium octanoate. technical background [0002] Chloroquine phosphate is a 4-aminoquinoline, which acts on the schizonts in the erythrocytes of Plasmodium, which may interfere with the replication and transcription process of Plasmodium schizont DNA or hinder its endocytosis, so that the parasites are Death due to lack of amino acids. For the treatment of chloroquine-sensitive falciparum malaria, vivax malaria and malaria malaria. And can be used for the suppressive prevention of malaria symptoms. It can also be used to treat parenteral amoebiasis, connective tissue disease, photosensitivity disease (such as sun erythema), etc...

Claims

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Application Information

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IPC IPC(8): A61K31/4706A61K47/22A61K47/10A61K47/18A61K47/12A61P33/06
CPCY02A50/30
Inventor 王进
Owner 天津市嘉凡生物科技有限公司
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