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Traditional Chinese medicine extract and preparation method thereof

A technology of extracts and natural medicines, applied in the directions of drug combinations, pharmaceutical formulations, anti-tumor drugs, etc., can solve the problems of malnutrition, dehydration of patients, acid-base balance disorders, etc., and achieve obvious synergies, increase inhibition, and enhance inhibition. effect of action

Inactive Publication Date: 2013-08-07
张宗升
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  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, etc., the incidence of chemotherapy-related diarrhea has increased year by year, and if active treatment is not carried out, it is easy to cause Dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc. in patients not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Therefore, effective treatment of chemotherapy-related diarrhea has become a An important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof

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Experimental program
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Effect test

Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of the concentrated extract of Astragalus and Scutellaria baicalensis decoction

[0036] According to the compatibility ratio of 1:1 or 1-4:1, take astragalus and scutellaria baicalensis, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and add the dregs 6 times of distilled water, soaking, decocting, and filtering in the same way, mixing the two filtrates, heating and concentrating to a small volume, filtering with an ultrafiltration membrane, and drying under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0037] (2) Preparation of astragalus polysaccharide

[0038] Astragalus is crushed, saponin is extracted with 95% ethanol and dried, then distilled water is added, saturated lime water is added drop by drop, the pH value is adj...

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Abstract

The invention relates to a natural medicine composition, a preparation method thereof, and an application thereof in preparing an attenuating and synergic medicine used in cancer chemotherapy. The natural medicine composition is composed of a Mongolian milkvetch root and Baikal skullcap root water decoction concentrate extract, astragalin, Baikal skullcap root total flavonoid, and baicalin according to a ratio of 2-5:2-6:3-7:4-7. The composition provided by the invention has an excellent treatment effect against cancer-chemotherapy-related diarrhea, and provides a synergetic effect for cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicinal composition, more specifically to a natural medicinal composition composed of Radix Astragali Radix and Scutellaria Radix Scutellariae decocted concentrated extract, astragalus polysaccharides, total flavonoids of Radix Scutellariae and baicalin, the preparation method of the natural medicinal composition and Use of the natural medicine composition for preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is currently one of the main diseases that endanger human survival and health. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemothe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61P1/12A61P35/00A61K31/7048A61K31/715
Inventor 张宗升
Owner 张宗升
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