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Dentrifice composition

A technology of composition and toothpaste, which is applied in the fields of dentistry, medical science, oral care, etc., can solve the problems of insufficient sterilization effect of bacteria inside the periodontal pathogenic biofilm, achieve prevention or improvement of periodontal disease, and good extrudability , the effect of improving performance

Active Publication Date: 2013-08-14
LION CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the combination of alginate with M / G ratio below 1.0 and triclosan can inhibit the formation of biofilm by increasing the oral retention of triclosan, but this technology is not effective for periodontal pathogenic biofilm bacteria. The bactericidal effect is not sufficient

Method used

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  • Dentrifice composition
  • Dentrifice composition
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Examples

Experimental program
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Embodiment

[0096] Next, the present invention will be specifically described by way of examples, comparative examples, and formulation examples, but the present invention is not limited to the following examples. Note: % in the following examples, unless otherwise specified, all refer to mass %.

[0097] [Example, Comparative Example]

[0098] The toothpaste compositions (mixed toothpastes) shown in Tables 1 and 2 were prepared according to the following method.

[0099] (Manufacturing method)

[0100] (1) Add (A) component: propylene glycol alginate and other water-soluble components (excluding binder and propylene glycol) to purified water, mix and dissolve them at room temperature, and prepare phase A.

[0101] (2) Add (B) component: isopropylmethylphenol to propylene glycol, dissolve it, add binder at normal temperature, and prepare B phase.

[0102] (3) While stirring phase A, phase C was prepared by adding and mixing prepared phase B thereinto.

[0103] (4) Add (C) component to...

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PUM

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Abstract

Provided is a dentrifice composition capable of sufficiently manifesting, after long-term storage, bactericidal effects against a periodontopathic biofilm formed by periodontal pathogenic bacteria in the oral cavity, and suppression of tooth surface adhesion by bacteria in the oral cavity, and also capable of effectively suppressing periodontopathic biofilm generation. The dentrifice composition is characterized by containing: (A) a propylene glycol alginate; (B) an isopropyl methyl phenol; and (C) at least one kind of non-ionic surfactant selected from a polyoxyethylene alkyl ether, with a C14-C18 alkyl group and an average number of moles of ethylene oxide added of 2 to less than 20, and a polyoxyethylene hydrogenated castor oil with an average number of moles of ethylene oxide added of 5-30.

Description

technical field [0001] The present invention relates to a toothpaste composition. The toothpaste composition has a strong bactericidal ability for the periodontal pathogenic biofilm formed by periodontal pathogenic bacteria in the oral cavity, and at the same time has the effect of inhibiting the bacteria in the oral cavity from adhering to the tooth surface. It can effectively exert its effect and inhibit the formation of periodontal pathogenic biofilm. Background technique [0002] Studies have shown that the two major oral problems of dental caries and periodontal disease are caused by various bacteria in the oral biofilm. In particular, dental caries is an infection caused by streptococci such as Streptococcus mutans (S. As for bad breath, it is related to oral bacteria such as Fusobacterium nucleatum (F.nucleatum). Therefore, as an effective means of preventing and improving oral diseases, the number of pathogenic bacteria in periodontal pathogenic biofilms can be kep...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/34A61K8/39A61K8/86A61Q11/00
CPCA61K8/733A61K8/39A61Q11/00A61K8/86A61K8/347A61K8/34A61K8/73
Inventor 近泽贵士森口纯
Owner LION CORP
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