Traditional Chinese medicine for treating hopatolenticular degeneration and its preparation method and use
A liver-type liver bean and nuclear degeneration technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve the short-term or long-term side effects of western medicine, patients unable to carry out maintenance treatment, and the condition of patients with liver type. Exacerbating problems such as reducing liver copper and serum copper content, regulating oxidation/antioxidant imbalance prevention and treatment, and achieving the effect of exact curative effect
Active Publication Date: 2014-11-26
杨文明
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Problems solved by technology
[0005] In the above-mentioned prior art, western medicine has unavoidable short-term or long-term toxic and side effects, making most patients unable to receive maintenance treatment, leading to gradual aggravation of the condition of patients with liver type, and even death
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specific Embodiment
[0034] The traditional Chinese medicine for treating liver-type hepatolenticular degeneration, wherein the raw materials are composed according to the following weight ratio:
[0035] Polygonum multiflorum (6g), wolfberry (12g), notoginseng (5g), smilax (30g), Bupleurum (10g), white peony root (12g), curcuma (6g), raw rhubarb (6g), daily dose of prescription: 87 grams
[0036] Preparation steps:
[0037] (1) Extract the Sanqi, Curcuma, and Rhubarb in the prescription with 80% ethanol for 2 to 3 times under reflux, 2 hours each time, filter, combine the ethanol extracts, reflux the ethanol under reduced pressure, and then further concentrate to a thick paste , vacuum or microwave drying.
[0038] (2) Add water to decoct the five medicinal materials of Polygonum multiflorum, Lycium barbarum, Smilax tuckahoe, Bupleurum, and Paeoniae Alba 3 to 4 times, each time for 1.5 to 2 hours, filter, combine the water extracts, concentrate under reduced pressure to a thick paste, vacuum or...
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The invention discloses a traditional Chinese medicine for treating hopatolenticular degeneration and its preparation method and use. The traditional Chinese medicine comprises, by mass, 6 parts of fleece-flower root, 12 parts of wolfberry, 5 parts of pseudo-ginseng, 30 parts of glabrous greenbrier rhizome, 10 parts of radix bupleuri, 12 parts of white peony root, 6 parts of curcuma rhizome and 6 parts of raw rhubarb. The preparation method comprises the following steps of carrying out backflow extraction of pseudo-ginseng, curcuma rhizome and raw rhubarb by ethanol, concentrating the extract into thick paste, carrying out vacuum or microwave drying, adding water into fleece-flower root, wolfberry, glabrous greenbrier rhizome, radix bupleuri and white peony root, carrying out decoction, concentrating the decoction into thick paste, carrying out vacuum or microwave drying to obtain dry extract, crushing the two types of the dry extract obtained by the above steps, adding dextrin or starch into the crushed dry extract, uniformly mixing, processing the mixture into a flexible material by ethanol as a wetting agent, and carrying out granulation, drying, finishing and split charging. The traditional Chinese medicine has effects of nourishing liver and kidney, sweeping phlegm and dispersing stasis, and supporting right and dispelling evil, and realizes simultaneous treatment of principal and subordinate symptoms. A large amount of clinical and basic studies prove that the traditional Chinese medicine has definite therapeutic effects.
Description
technical field [0001] The invention relates to a medicine for treating hepatolenticular degeneration, in particular to a traditional Chinese medicine for treating hepatic hepatolenticular degeneration, a preparation method and application thereof. Background technique [0002] Hepatolenticular degeneration, also known as Wilson's disease, is an autosomal recessive disorder of copper metabolism. It is caused by a mutation in the ATP7B gene that leads to abnormal copper metabolism in the body, and excessive copper deposition in tissues such as the liver and brain. Syndrome of clinical manifestations. [0003] Hepatolenticular degeneration is mainly divided into liver type, cerebral type and brain-visceral type. For patients with liver type, hepatic fibrosis, cirrhosis, fulminant hepatic failure and death are prone to occur. So far, there have been great breakthroughs in the treatment of hepatolenticular degeneration, but the treatment of hepatic degeneration is still the fo...
Claims
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IPC IPC(8): A61K36/9066A61P1/16A61P3/00
Inventor 杨文明汪瀚汪美霞鲍远程
Owner 杨文明