Self-heating microfluidic chip

A microfluidic chip, self-heating technology, used in heating or cooling equipment, laboratory utensils, laboratory containers, etc., can solve problems such as expensive, affecting the promotion of microfluidic chips, complex peripherals, etc. easy effect

Inactive Publication Date: 2013-09-18
苏州扬清芯片科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned heating method has the following disadvantages: either complex peripherals are required, or the preparation process is cumbersome and expensive
These shortcomings have affected the promotion of microfluidic chips, especially in some micro-analysis applications that require portability of instruments and equipment.

Method used

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  • Self-heating microfluidic chip
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1 A self-heating microfluidic chip

[0014] A self-heating microfluidic chip is prepared from polymethyl methacrylate. like figure 1 As shown, the chip has a five-layer structure, in which the thickness of the cover layer is 1mm, and a fluid inlet and outlet with a diameter of 3mm is processed; the thickness of the microfluidic layer is 0.5mm, and hollowed out microfluidic channels and chambers are processed; the middle heat transfer layer is blank Polymethyl methacrylate film with a thickness of 0.1mm; self-heating layer with a thickness of 0.5mm, processed with the same hollow structure as the microfluidic layer, filled with calcium oxide microspheres with a particle size of 200μm; the base layer with a thickness of 1mm, processed with a diameter The 3mm fluid inlet and outlet provide channels for water to flow in and fill the entire self-heating layer and have an exothermic reaction with the calcium oxide filler. The five-layer structure is aligned and stac...

Embodiment 2

[0015] Example 2 A self-heating microfluidic chip with internal storage of water

[0016] A self-heating microfluidic chip is prepared from polymethyl methacrylate, and its self-heating layer structure is as follows: figure 2 As shown, the interior is stored with water and calcium oxide filler. Wherein, water is sealed in chamber a in the chip; calcium oxide microspheres are also sealed in another chamber c in the chip. The two chambers are isolated by a screw-type isolating valve b. When in use, the isolating valve is opened, and water flows into the calcium oxide chamber to undergo an exothermic reaction, thereby realizing self-heating of the microfluidic chip.

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Abstract

The invention provides a self-heating microfluidic chip which is integrally heated in an integral self-heating system in the microfluidic chip. The microfluidic chip is composed of a cover plate layer, a microfluidic layer, a heat transfer layer, a self-heating layer and a basal layer. The working principle of the self-heating type microfluidic chip is as follows: water is injected into the self-heating layer, and a self-heating effect is obtained by carrying out an exothermic reaction on the water and calcium oxide. By using the self-heating method provided by the invention, a heater is not needed, the operation is simple and convenient, and the self-heating method is especially suitable for a portable micro total analysis system.

Description

technical field [0001] The invention relates to a microfluidic chip, in particular to a self-heating microfluidic chip. Background technique [0002] In recent years, microfluidic chip technology has been widely researched and applied in the fields of biology, chemistry, and medicine. In the application process of microfluidic chips, many chemical and biological reactions and detections often need to be carried out under specific temperature conditions. Therefore, heating control is of great significance in the application of microfluidic chips. At present, the heating of the microfluidic chip is mainly realized by relying on an external heating plate or integrating a microelectrode array prepared for heating in the microfluidic chip. However, the above-mentioned heating method has the following disadvantages: either complex peripheral equipment is required, or the preparation process is cumbersome and expensive. These shortcomings have affected the promotion of microflui...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00B01L7/00
Inventor 叶嘉明
Owner 苏州扬清芯片科技有限公司
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