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Optical coherence tomography method and optical coherence tomography system for complex polarization frequency domain

A technology of optical coherence tomography, imaging method, applied in the direction of polarization influence characteristics, etc., can solve the problems of reduced image sensitivity and expensive system

Active Publication Date: 2013-10-09
SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI
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Problems solved by technology

This method uses electro-optic modulation devices to generate left and right circularly polarized light to image samples with birefringence properties. The system is expensive and the trigger signals of CCD and electro-optic modulation devices need to be strictly controlled.
At the same time, due to the use of linear phase modulation, as the horizontal scanning range increases, the image sensitivity decreases

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  • Optical coherence tomography method and optical coherence tomography system for complex polarization frequency domain
  • Optical coherence tomography method and optical coherence tomography system for complex polarization frequency domain
  • Optical coherence tomography method and optical coherence tomography system for complex polarization frequency domain

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[0066] The present invention will be further described below in conjunction with the examples and drawings, but the examples should not limit the protection scope of the present invention.

[0067] see figure 1 . figure 1 It is a schematic structural diagram of a polarization-complex frequency-domain optical coherence tomography system with sinusoidal phase modulation in the present invention. A polarization frequency-domain optical coherence tomography system with sinusoidal phase modulation, comprising a low-coherence light source 1, a collimator beam expander 2, a polarizer 3, and a Michelson interferometer 4 are sequentially placed in the illumination direction of the low-coherence light source 1, The non-polarizing beam splitter 41 of the Michelson interferometer 4 divides the incident line polarized light into a reference arm optical path 42 and a sample arm optical path 43, and the reference arm optical path is followed by a quarter-wave plate 44 and a reference plane ...

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Abstract

The invention discloses an optical coherence tomography method and an optical coherence tomography system for a complex polarization frequency domain. The method comprises the following steps of: on the basis of optical coherence tomography of a polarization frequency domain, driving a reference plane mirror of a reference arm to vibrate by a phase modulation device, introducing sinusoidal phase modulation while transversely scanning a sample, performing processing such as Fourier transform on acquired interference signals of horizontal and vertical polarization channels to obtain chromatography signals of the horizontal and vertical polarization channels without parasitic images, extracting magnitudes and phases of the chromatography signals respectively, and calculating to obtain an intensity image, a fast axis image and a delay image of the sample with double refraction properties within a full-depth range. According to the method, the imaging speed is high, a complex conjugate mirror image, a direct-current background and the self-coherence noise in the coherent tomography of the polarization frequency domain are removed, the sensitivity cannot be reduced along with the prolonging of a transverse scanning distance, and the method is not sensitive to motion blur in the sample.

Description

technical field [0001] The present invention relates to frequency-domain optical coherence tomography (Fourier-Domain Optical Coherence Tomography, referred to as FD-OCT), in particular to a polarization complex frequency-domain optical coherence tomography method and system. Background technique [0002] Optical Coherence Tomography (OCT) is a biomedical tomography technology based on low-coherence light interference. It has high resolution and non-invasiveness, and can perform non-destructive detection of biological tissues within a few millimeters in depth. . After Huang et al. proposed this concept in 1991 (see prior art [1], D.Huang, E.A.Swanson, C.P.Lin, J.S.Shuman, W.G.Stinson, W.Chang, M.R.Hee, T.Flotte, K.Gregory, C.A.Puliafito and J.G.Fujimoto, "Optical coherence tomography", Science, Vol.254, pp.1178-1181, 1991), OCT is widely used in the diagnosis and research of ophthalmology, skin, cardiovascular and other fields. [0003] Frequency-domain optical coherence t...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/21
Inventor 陈艳王向朝李中梁南楠郭昕王瑄
Owner SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI
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