Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Degradable bone regeneration guidance biomembrane, preparation method and application thereof

A technology for guiding bone regeneration and biofilm, applied in medical science, surgery, etc., can solve the problems of bone degradation mismatch, easy collapse, infection, etc., and achieve the goal of maintaining bone regeneration space, good strength performance indicators, and promoting bone regeneration Effect

Inactive Publication Date: 2013-10-16
JILIN UNIV
View PDF3 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there are still some problems in the application of today's biofilms, such as: non-absorbable films can easily cause soft tissue valve cracking, exposure of the film, and infection; Large tension, premature degradation and osteogenesis mismatch, expensive, etc., difficult to meet various clinical needs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Degradable bone regeneration guidance biomembrane, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0034] The specific content and implementation of the technical solution of the present invention will be further described below in conjunction with examples.

[0035] The selection range of biofilm-forming materials and content (W / V) for guided bone regeneration is as follows:

[0036] material ingredient

content

poly(1,2-propylene carbonate)

5—8g

polybutylene succinate

5—8g

[0037] Preparation method of a degradable guided bone regeneration biofilm

[0038] Weigh poly(1,2-propylene carbonate) and poly(butylene succinate) in a certain proportion, dissolve them in an organic solvent, stir with a magnetic stirrer to dissolve completely, form a cloudy liquid, add salt, stir to make it evenly distributed in the In the cloudy liquid, pour the cloudy liquid into a special mold. Stand in the air for 4-96 hours to volatilize and remove the organic solvent to form a composite biofilm containing salt particles, rinse in deionized water for...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
pore sizeaaaaaaaaaa
Login to View More

Abstract

The present invention discloses a degradable bone regeneration guidance biomembrane, a preparation method and an application thereof. According to the present invention, propylene carbonate and poly(butylene succinate) are weighed according to a certain ratio as raw materials, and are dissolved into an organic solvent to prepare a turbid solution, and a salting out method is adopted to synthesize a biomembrane; the biomembrane is mainly applicable for stomatological implant dental department, wherein a bone regeneration space can be long-lastingly maintained and bone regeneration can be promoted in the application of the stomatological department bone defect case; and compared with the biomembrane and the preparation method thereof in the prior art, the biomembrane and the preparation method thereof of the present invention have the following characteristics that: the double layer-like structure similar to the human periosteum can be synthesized through the salting out method, the biomembrane has characteristics of good physical and chemical properties, in vitro bone regeneration guidance bioactivity, low price and the like, a plurality of shortcomings of the existing clinically used biomembrane can be overcome so as to provide an effective biomembrane for stomatological implant dental department clinic and promote bon regeneration, wherein the shortcomings comprise thick biomembrane, large tissue tension in the surgery region, easy wound dehiscence and the like.

Description

technical field [0001] The invention relates to a degradable guiding bone regeneration biofilm and its preparation method and application, which belongs to biodegradable materials and is mainly used in the field of oral implant dentistry. Background technique [0002] Implant dentures are known as the third set of teeth for human beings. Their comfort and aesthetics similar to real teeth are becoming more and more accepted by patients. They are highly recommended by more and more clinicians and have become a routine treatment for tooth loss restoration. means. However, a considerable number of edentulous patients have insufficient alveolar bone or jaw bone defects, which limit the development of dental implant technology. Bone grafting and / or guided bone regeneration are often needed to solve this problem. Bone grafting often needs to be combined with guided bone regeneration. [0003] The principle of Guided Bone Regeneration (GBR) is to use the physical barrier function ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/14
Inventor 储顺礼冯超周延民李楚
Owner JILIN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com