The present invention discloses a degradable
bone regeneration guidance biomembrane, a preparation method and an application thereof. According to the present invention,
propylene carbonate and poly(butylene succinate) are weighed according to a certain ratio as raw materials, and are dissolved into an
organic solvent to prepare a turbid solution, and a
salting out method is adopted to synthesize a biomembrane; the biomembrane is mainly applicable for stomatological
implant dental department, wherein a
bone regeneration space can be long-lastingly maintained and
bone regeneration can be promoted in the application of the stomatological department
bone defect case; and compared with the biomembrane and the preparation method thereof in the prior art, the biomembrane and the preparation method thereof of the present invention have the following characteristics that: the double layer-like structure similar to the human
periosteum can be synthesized through the
salting out method, the biomembrane has characteristics of good physical and chemical properties,
in vitro bone regeneration guidance bioactivity, low price and the like, a plurality of shortcomings of the existing clinically used biomembrane can be overcome so as to provide an effective biomembrane for stomatological
implant dental department clinic and promote bon regeneration, wherein the shortcomings comprise thick biomembrane, large tissue tension in the
surgery region, easy wound dehiscence and the like.