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Formula and preparation process of traditional Chinese medicine for treating ulcerative colitis

A technology for ulcerative colitis and traditional Chinese medicine, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, can solve the problems of increased side effects of medication, unsatisfactory curative effect in refractory patients, and easy recurrence, etc. The effect of easy operation and control, low energy consumption, and simple method

Inactive Publication Date: 2013-10-23
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although aminosalicylic acid drugs and corticosteroids are still the main drugs for the treatment of ulcerative colitis, they have the advantages of quick onset and high short-term clinical remission rate, but they are prone to relapse after drug withdrawal, and the side effects of long-term medication increase. Unsatisfactory curative effect for refractory patients

Method used

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  • Formula and preparation process of traditional Chinese medicine for treating ulcerative colitis
  • Formula and preparation process of traditional Chinese medicine for treating ulcerative colitis
  • Formula and preparation process of traditional Chinese medicine for treating ulcerative colitis

Examples

Experimental program
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Effect test

specific Embodiment 1

[0044] Specific embodiment 1: granule

[0045] Prescription: 1000 grams of white peony, 900 grams of skullcap, 900 grams of coptis, 600 grams of cork, 1000 grams of angelica, 500 grams of woody fragrance, 1000 grams of Dabupi

[0046] (1) Grind Radix Paeoniae Alba into very fine powder, pass through a 120-mesh sieve for later use.

[0047] (2) Angelica sinensis and Muxiang were respectively refluxed once with 6 times and 4 times the amount of 95% ethanol, each time for one hour, filtered in stages, combined filtrates, concentrated to a relative density of 1.04 for later use.

[0048] (3) Merge the medicinal dregs after alcohol extraction in step (2) into Coptidis Rhizome, Phellodendron Phellodendri, and Dabupi, add water to soak for half an hour, add 10 times the amount of water for the first time, add Scutellaria baicalensis after boiling, and decoct for 2 hours , add 8 times the amount of water for the second time, decoct for 1 hour, filter separately, combine the filtrates...

specific Embodiment 2

[0050] Specific embodiment 2: capsule

[0051] Prescription: 1000 grams of white peony, 900 grams of skullcap, 900 grams of coptis, 600 grams of cork, 1000 grams of angelica, 500 grams of woody fragrance, 1000 grams of Dabupi

[0052] (1) Grind Radix Paeoniae Alba into very fine powder, pass through a 120-mesh sieve for later use.

[0053](2) Angelica sinensis and Muxiang were respectively refluxed once with 6 times and 4 times the amount of 95% ethanol, each time for one hour, filtered in stages, combined filtrates, concentrated to a relative density of 1.04 for later use.

[0054] (3) Merge the medicinal dregs after alcohol extraction in step (2) into Coptidis Rhizome, Phellodendron Phellodendri, and Dabupi, add water to soak for half an hour, add 10 times the amount of water for the first time, add Scutellaria baicalensis after boiling, and decoct for 2 hours , add 8 times the amount of water for the second time, decoct for 1 hour, filter separately, combine the filtrates,...

specific Embodiment 3

[0056] Specific embodiment 3: tablet

[0057] Prescription: 1000 grams of white peony, 900 grams of skullcap, 900 grams of coptis, 600 grams of cork, 1000 grams of angelica, 500 grams of woody fragrance, 1000 grams of Dabupi

[0058] (1) Grind Radix Paeoniae Alba into very fine powder, pass through a 120-mesh sieve for later use.

[0059] (2) Angelica sinensis and Muxiang were respectively refluxed once with 6 times and 4 times the amount of 95% ethanol, each time for one hour, filtered in stages, combined filtrates, concentrated to a relative density of 1.04 for later use.

[0060] (3) Merge the medicinal dregs after alcohol extraction in step (2) into Coptidis Rhizome, Phellodendron Phellodendri, and Dabupi, add water to soak for half an hour, add 10 times the amount of water for the first time, add Scutellaria baicalensis after boiling, and decoct for 2 hours , add 8 times the amount of water for the second time, decoct for 1 hour, filter separately, combine the filtrates,...

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Abstract

The invention relates to a formula and preparation process of a traditional Chinese medicine for treating ulcerative colitis. The formula of the traditional Chinese medicine for treating ulcerative colitis comprises the following components in parts by weight: 8-15 parts of radix paeoniae alba, 6-15 parts of Scutellaria baicalensis, 3-15 parts of Coptis chinensis, 3-12 parts of golden cypress, 6-15 parts of Angelica sinensis, 6-18 parts of pericarpium arecae and 3-12 parts of elecampane. The traditional Chinese medicine provided by the invention has the functions of clearing away heat and toxic materials, eliminating dampness, replenishing qi to invigorate the spleen and adjusting qi and blood; therefore, the formula is the optimum formula for treating ulcerative colitis. Clinical researches of the traditional Chinese medicine formula for treating ulcerative colitis display that the formula has remarkable advantages in clinical comprehensive curative effect, traditional Chinese medicine syndrome curative effect, curative effect of colonoscopy and Geboes exponential integral and is free of remarkable adverse reaction, thereby adequately displaying the superiority of the traditional Chinese medicine for treating ulcerative colitis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine formula for treating ulcerative colitis and a preparation process. Background technique [0002] The etiology of ulcerative colitis is currently unknown, and the effect of non-surgical therapy is unsatisfactory. So far, there are still problems such as many complications, high mortality, many chances of canceration, high operation rate and recurrence rate. The treatment of UC in modern medicine mainly starts from the following aspects: one is to eliminate the incentives, such as avoiding mental stress, improving diet structure, etc.; Check cure. The drugs used include aminosalicylic acids, corticosteroids, immunosuppressant antibacterials, etc., among which aminosalicylic acids include sulfasalazine (SASP) and 5-aminosalicylic acid (5-ASA) , its therapeutic mechanism is currently believed to be related to the inhibition of natural killer cell activity, inhibition of antibodies, leukotrienes and ...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P1/04
Inventor 何永恒胡晓丹林仁敬喻融李艳华
Owner HUNAN UNIV OF CHINESE MEDICINE
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