Traditional Chinese medicine effective part composition for treating schizophrenia and preparation method thereof

A technology for schizophrenia and effective parts, which is applied in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve the problems of prolonged disease course, high relapse rate, and chronic decline of patients, and achieve no toxic and side effects, maintain The effect of simple active ingredients and preparation methods

Inactive Publication Date: 2014-09-03
广州市云桥生物科技有限公司
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the recurrence rate of this disease is relatively high, and some patients have a prolonged course of disease and may develop into a chronic decline state.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take 25g of lotus seeds, 29g of Sichuan Achyranthes bidentata, 18g of bamboo ginseng, 18g of musk shell and 10g of castor bean, grind them into coarse powder, add 12 times the amount of water, decoct 3 times, each time for 1 hour; filter the decoction and combine The filtrate was concentrated under reduced pressure to a paste with a relative concentration of 1.14, and ethanol was added to make the alcohol content 69%, and it was allowed to stand overnight, and the ethanol was recovered to obtain 1000ml of the concentrated solution. Adjust the pH to 4, add distilled water to 5000ml, stir evenly, filter and pack into 15ml glass bottles, and pack to obtain oral liquid.

[0019] This product is a yellow-brown clear liquid, which will not become turbid within half a year, with a pH of about 4 and a total solid of about 9%.

Embodiment 2

[0021] 200 patients were clinically observed, all of whom had obvious clinical symptoms of schizophrenia and were diagnosed by clinicians.

[0022] Oral the oral liquid that embodiment 1 makes, every day 2 times, each 15ml. Medication time is 30 days.

[0023] After 30 days, the statistical results of patients using the oral liquid obtained in Example 1 are shown in Table 1.

[0024] Efficacy standard: Marked effect includes recovery and improvement, among which, recovery refers to the disappearance of symptoms, recovery of insight, good response to the surrounding environment, and recovery of work, study and living ability before the disease; improvement refers to the basic disappearance of symptoms of the patient, self-knowledge Most of the strength recovered, and the ability to work and study before the illness was basically restored. Ineffective means no improvement or even worsening of symptoms.

[0025] Table 1

[0026] Number of cases markedly effective ...

Embodiment 3

[0029] The oral liquid prepared in Example 1 was used to administer ICR mice with a body weight of 20-25 g, half male and half male, and the administration was continued for 90 days.

[0030] After pre-testing, the toxicity of the lotion prepared in Example 1 was very low, and the LD50 could not be measured, so the maximum daily dose was determined for mice. The maximum dosage is 150ml / d. After 90 days, there is no case of poisoning death, and all of them are alive and healthy. This proves that the oral liquid made from the composition of the present invention will not cause toxic and side effects to the human body.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a traditional Chinese medicine effective part composition for treating schizophrenia and a preparation method thereof. The traditional Chinese medicine effective part composition of the invention is made from lotus seeds, achyranthes bidentata, bamboo ginseng, musk shell and castor bean in certain parts by weight. The composition of effective parts of the traditional Chinese medicine described in the present invention can be prepared as a medicine for treating schizophrenia. The effect of the spleen can significantly treat schizophrenia, and has the advantages of no toxic side effects and high safety.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition of active parts of traditional Chinese medicines for treating schizophrenia and a preparation method thereof. Background technique [0002] Schizophrenia is the most common of all mental illnesses. Its main clinical features are changes in basic personality, splits in thinking, emotion, and behavior, and incoordination between mental activities and the environment. At present, the etiology and pathogenesis of schizophrenia have not yet been elucidated, and there is no special treatment. The treatment methods commonly used in modern Western medicine are antipsychotic drugs, insulin shock, electroshock and psychotherapy. However, the recurrence rate of the disease is high, and some patients have a prolonged course of disease and can develop into a chronic decline state. Contents of the invention [0003] The object of the present invention...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/62A61P25/18A61K35/55
Inventor 张群
Owner 广州市云桥生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap