Tibetan-medicine three-component Tibet inula soup-granula composition and preparation process thereof

A preparation process and granule technology, which are applied in the field of Tibetan medicine Sanwei Zangmuxiangtang granule formulation and the field of preparation technology, can solve the problems of different quantities, uncontrollable quality, inconvenient taking, etc. The effect of meeting clinical drug needs, improving labor productivity, and taking convenience

Inactive Publication Date: 2014-02-19
多杰 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Through pharmacological tests, the present invention determines the formula quantity, verifies the effectiveness and safety, adopts modern pharmaceutical equipment and technologies such as ultrafine pulverization, vacuum drying, centrifugal spray drying, etc., and invents a stable process, controllable quality, safe and effective, edible The convenient new Tibetan medicine granule preparation solves the problems of different prescriptions of Sanwei Zangmuxiang Decoction, backward technology, uncontrollable quality, and inconvenience in taking.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Prescription: 1%-300% of Rubus wood, 2%-160% of broad tendon rattan, 4%-180% of Tibetan woody fragrance;

[0032] Preparation process: Weigh the amount of Zangmuxiang in the recipe, place it in an ultrafine pulverizer for 90 minutes, and pass through a 140-mesh sieve for later use. Put the vine and raspberry in a multifunctional extraction tank, add 8 times the amount of clean water, decoct and extract 4 times, each extraction time is 3 hours, combine the filtrate, concentrate to a relative density of 1.3 or more, and use centrifugal spray Dryer dry. The dry paste powder and the micro-powder of Akira samanthus are weighed according to a weight ratio of 1:1, mixed, and 85% ethanol is added to make a soft material, which is granulated by a granulator, dried, granulated, and packaged.

Embodiment 2

[0034] Prescription: 1%-300% of Rubus wood, 2%-160% of broad tendon rattan, 4%-180% of Tibetan woody fragrance;

[0035] Preparation process: Weigh the amount of Zangmuxiang in the recipe, place it in an ultrafine pulverizer for 30 minutes, and pass through a 100-mesh sieve for later use. Put the vine and raspberry in a multi-functional extraction tank, add 6 times the amount of clean water, decoct and extract once, each extraction time is 8h, combine the filtrate, concentrate to a relative density of 1.3 or more, and use centrifugal spray Dryer dry. Weigh the dry cream powder and the micro-powder of Akira sinensis according to the weight ratio of 1:8, mix them, add 65% ethanol, make a soft material, put it into a granulator to granulate, dry, granulate, and pack.

Embodiment 3

[0037] Prescription: 1%-300% of Rubus wood, 2%-160% of broad tendon rattan, 4%-180% of Tibetan woody fragrance;

[0038]Preparation process: Weigh the amount of Zangmuxiang in the recipe, place it in an ultrafine pulverizer for 300 minutes, and pass through a 200-mesh sieve for later use. Put the vine and raspberry in a multi-functional extraction tank, add 10 times the amount of clean water, decoct and extract 9 times, each extraction time is 1h, combine the filtrate, concentrate to a relative density of 1.3 or more, and use centrifugal spray Dryer dry. The dry paste powder and the micro-powder of Akira samanthus are weighed according to a weight ratio of 1:1, mixed, added with 100% ethanol, made into a soft material, granulated by a granulator, dried, granulated, and packaged.

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PUM

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Abstract

The invention relates to a Tibetan medicine, and particularly relates to a Tibetan-medicine three-component Tibet inula soup-granula composition and a preparation process thereof. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: Ramulus Rubi, Tinospora sinensis and Tibet inula in a proportion of 2:1:1. The preparation process comprises the following steps: 1) carrying out superfine grinding on the Tibet inula; 2) placing the Tinospora sinensis and the Ramulus Rubi in a multifunctional extraction pot to decoct, filtering and concentrating to obtain an aqueous extract, and drying the aqueous extract by using a centrifugal spray drier; 3) combining dry cream powder with micro-powder; and 4) adding ethanol into the obtained powder, preparing into a soft material, granulating the soft material by using a granulator, drying, and carrying out straightening granulation to obtain the composition. According to the composition disclosed by the invention, when the quality of Tibetan medicines is improved, due to the reference and introduction of some new processes, new techniques and new devices, the stability and bioavailability of preparations can be improved, and traditional Tibetan medicine and modern preparation methods are combined, thus a way for the rational development of Tibetan medicines is explored.

Description

1. Technical field: [0001] The technology of the present invention belongs to the field of Tibetan medicine pharmacy, and in particular relates to a granule prescription of Tibetan medicine Sanwei Zangmuxiangtang and a preparation process thereof. 2. Background technology: [0002] Sanwei Zangmuxiangtang Granule is a new type of Tibetan medicine granule preparation invented on the basis of the traditional Tibetan medicine prescription "Sanwei Zangmuxiangtang" through pharmacological experiments and preparation technology research. The Sanwei Zangmuxiangtang recipe originated from "Thousands of Relics" written by Suka Nianmu Dorje, the founder of the Southern School of Tibetan Medicine in the 15th century AD. Composed of rattan three-flavored medicine, it has the effect of clearing wind-heat and regulating blood flow; it is used for fever caused by wind-heat and blood flow disorders, thirst, dry mouth, pain in acupoints, chest air resistance, fullness, and shortness of breath...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61K36/59A61K9/16A61P29/00A61P11/00
Inventor 多杰赛桑杰多杰拉旦尼玛才让
Owner 多杰
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