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Application of compound thrombosis capsule in aspect of kidney protection

A compound Xueshuantong and capsule technology, applied in capsule delivery, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve problems such as kidney protection, reduce inflammation levels, reduce fibrin deposition, and have no toxic side effects. Effect

Inactive Publication Date: 2014-03-26
GUANGDONG ZHONGSHENG PHARMA +1
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Problems solved by technology

[0005] The purpose of the present invention is to provide the use of Compound Xueshuantong Capsules in protecting the kidneys, aiming to solve the problem of kidney protection in the treatment of cardiovascular diseases

Method used

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  • Application of compound thrombosis capsule in aspect of kidney protection
  • Application of compound thrombosis capsule in aspect of kidney protection
  • Application of compound thrombosis capsule in aspect of kidney protection

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Embodiment Construction

[0012] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0013] The present invention conducts experiments on the rat disseminated intravascular coagulation model induced by lipopolysaccharide, and finds that Fufang Xueshuantong Capsule not only has the effects of significantly improving blood rheological constants and blood coagulation functions, but also has the remarkable effect of protecting the kidneys. The role of the function. Fufang Xueshuantong Capsules can significantly inhibit the increase of renal function biochemical indicators urea nitrogen and creatinine levels, reduce the level of renal inflammation induced by lipopolysaccharide, and redu...

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Abstract

The invention is applicable to the field of Chinese patent medicines. A lipopolysaccharide-induced rat diffuse intravascular coagulation model is adopted for experimenting, and the experiment result shows that a compound thrombosis capsule can significantly inhibit the rise of kidney-function biochemical indexes including urea nitrogen level and creatinine level, reduces the level of lipopolysaccharide-induced kidney inflammation, and reduces fibrous deposition in a glomeruli. The experiment proves that the compound thrombosis capsule performs the function of protecting a kidney and does not have toxic or side effects. The compound thrombosis capsule can be used for kidney protection in vascular disease treatment in a clinical center.

Description

technical field [0001] The invention belongs to the field of Chinese patent medicines, and in particular relates to the use of compound Xueshuantong capsules in protecting kidneys. Background technique [0002] Studies have shown that kidney function is closely related to cardiovascular disease. The kidney is an important organ of the human body. Its main function is to remove excess water and waste from the body through the formation of urine. After the formation of microthrombosis in cardiovascular diseases, the fibrinolytic activity is secondary enhanced, leading to the increase of fibrin degradation products. Most of these fiber metabolites are excreted with urine through glomerular blood filtration and renal tubule secretion. Therefore, a large number of microthrombus deposits are easily formed in the glomerulus, which eventually leads to impaired excretory function of the kidney. At the same time, sodium and water retention and uremia are prone to occur after impair...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61K9/48A61P9/00A61P13/12A61P29/00
Inventor 苏薇薇生书晶谢称石龙超峰王锦旭刘宏李沛波王永刚彭维
Owner GUANGDONG ZHONGSHENG PHARMA
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