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Preparation method of Chinese medicinal composition and Chinese medicinal composition prepared by using preparation method

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine preparations, can solve problems such as differences in the types, structures, and physical and chemical properties of active ingredients, and achieve the effects of improving microcirculation, improving curative effect, and improving extraction methods

Active Publication Date: 2014-04-23
BEIJING HANDIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] This process extracts all the twelve traditional Chinese medicines in the prescription with water, without taking into account the differences in the types, structures, and physical and chemical properties of the active ingredients of different medicinal materials

Method used

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  • Preparation method of Chinese medicinal composition and Chinese medicinal composition prepared by using preparation method
  • Preparation method of Chinese medicinal composition and Chinese medicinal composition prepared by using preparation method
  • Preparation method of Chinese medicinal composition and Chinese medicinal composition prepared by using preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Example 1 A Gentongping Granule

[0043] The raw material drug prescription is:

[0044] 200g of white peony root, 50g of kudzu root, 50g of peach kernel, 50g of safflower, 50g of vinegar-roasted frankincense, 50g of vinegar-roasted myrrh, 75g of Dipsacus, 75g of scalded dog spine, 75g of Shenjincao, 50g of Achyranthes bidentata, 50g of rehmannia glutinosa, 25g of licorice

[0045] Prepared by:

[0046] (1) Prepare various medicinal materials according to the prescription.

[0047](2) Take frankincense and myrrh and add 1 kg of water (10 times the amount), extract the volatile oil by steam distillation for 5 hours, collect the distilled aqueous solution in another device, and prepare the dregs for later use; add an appropriate amount of absolute ethanol to dissolve the volatile oil, and weigh β-cyclodextrin with 6 times the volume of volatile oil, add water 20 times the weight of β-cyclodextrin, mix well to obtain β-cyclodextrin aqueous solution; Add the volatile o...

Embodiment 2

[0052] Example 2 A Gentongping Granule

[0053] API prescription:

[0054] 100g of white peony root, 25g of kudzu root, 25g of peach kernel, 25g of safflower, 25g of vinegar-roasted frankincense, 25g of vinegar-roasted myrrh, 45g of Dipsacus, 45g of scalded dog spine, 45g of Shenjincao, 25g of Achyranthes bidentata, 25g of rehmannia glutinosa, 15g of licorice

[0055] Prepared by:

[0056] (1) Prepare various medicinal materials according to the prescription.

[0057] (2) Take frankincense and myrrh and add 0.5kg of water (10 times the amount), extract the volatile oil by steam distillation for 5 hours, collect the distilled aqueous solution in another device, and use the dregs for later use; dissolve the volatile oil with an appropriate amount of absolute ethanol, and weigh it Add β-cyclodextrin that is 4 times the volume of volatile oil, add water 16 times the weight of β-cyclodextrin, and mix well to obtain an aqueous solution of β-cyclodextrin; Add the volatile oil et...

Embodiment 3

[0062] Example 3 A Gentong Tablet

[0063] API prescription:

[0064] 300g of white peony root, 75g of kudzu root, 75g of peach kernel, 75g of safflower, 75g of vinegar-roasted frankincense, 75g of vinegar-roasted myrrh, 105g of Dipsacus, 105g of scalded dog spine, 105g of Shenjincao, 75g of Achyranthes bidentata, 75g of rehmannia glutinosa, 35g of licorice

[0065] Prepared by:

[0066] (1) Prepare various medicinal materials according to the prescription.

[0067] (2) Take frankincense and myrrh and add 1.5kg of water (10 times the amount), extract the volatile oil by steam distillation for 5 hours, and collect the distilled aqueous solution in another device; times the β-cyclodextrin, add water 20 times the weight of the β-cyclodextrin, and mix evenly to obtain an aqueous solution of β-cyclodextrin; at a speed of 150 rpm, slowly add After adding the volatile oil ethanol solution, continue to stir for 0.5 hours, refrigerate for 12 hours, filter, and dry the filtered pro...

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Abstract

The invention provides a preparation method of a Chinese medicinal composition. The Chinese medicinal composition consists of the following bulk pharmaceuticals in parts by weight: 100-300 parts of white paeony root, 25-75 parts of kudzuvine root, 25-75 parts of hot-water-soaked peach kernel, 25-75 parts of safflower, 25-75 parts of vinegar-roasted frankincense, 25-75 parts of vinegar-roasted myrrh, 45-105 parts of himalayan teasel root, 45-105 parts of heated east Asian tree fern rhizome, 45-105 parts of common clubmoss herb, 25-75 parts of twotooth achyranthes root, 25-75 parts of rehmannia and 15-35 parts of liquoric root. The preparation method comprises the steps of extracting volatile oil from the frankincense and myrrh, and including the volatile oil with beta-cyclodextrin; heating the decoction dregs of the frankincense and myrrh together with the other bulk pharmaceuticals with an ethanol aqueous solution and water respectively, and performing reflux extraction. The invention further provides a Chinese medicinal composition prepared by using the preparation method. Compared with the prior art, the preparation method has the advantages that active ingredients can be extracted more completely, and the medicinal effect is enhanced remarkably.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a new preparation method of Gentongping, a Chinese medicine composition used for cervical and lumbar spondylosis caused by wind-cold blockage of collaterals. Background technique [0002] Gentongping Granules, the prescription comes from "Chinese Pharmacopoeia" (page 986 of the first volume), composed of white peony root, kudzu root, peach kernel, safflower, frankincense (roasted with vinegar), myrrh (roasted with vinegar), Dipsacus, dog spine (Hot), Shenjincao, Achyranthes bidentata, Rehmannia glutinosa, and licorice are composed of 12 Chinese herbal medicines. They have the effects of promoting blood circulation, dredging collaterals, and relieving pain. They are used for neck and lumbar spondylosis caused by wind-cold obstruction. Limitation, numbness of upper extremities. The preparation process recorded in the Pharmacopoeia is: decocting ...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/16A61P29/00A61P25/02A61P19/08
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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