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A kind of preparation method of medicament for treating pain after neurosurgery

A neurosurgery and drug technology, which can be used in drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as unfavorable local nerve recovery, mask disease, etc., and achieve the effect of reducing the expression of NMDA receptors

Inactive Publication Date: 2016-04-13
CHONGQING TIANYI HENGHUA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, in this case, the use of analgesic drugs after surgery will often cover up the condition and is not conducive to the recovery of local nerves.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1, raw material drug weight ratio: 20 parts of fig leaves, 10 parts of sarcophagus, 6 parts of bamboo yellow, 10 parts of aescin, 6 parts of bellflower, 10 parts of Peucedanum, 10 parts of wax gourd seeds, 10 parts of hops 10 parts of black plum, 2 parts of Shujincao, 6 parts of papaya, 20 parts of white horse bone.

[0032] The preparation method of embodiment 1 is: mix ficus leaf, sarcophagus, bamboo yellow, aescin, platycodon, peucedanum, wax gourd seeds, hops, ebony plum, tendons-relieving grass, papaya, white horse bone and add water to decoct, Take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide into two parts and take it in the morning and evening.

Embodiment 2

[0033] Example 2, raw material drug weight ratio: 10 parts of fig leaves, 6 parts of sarcophagus, 3 parts of bamboo yellow, 6 parts of Aescin, 3 parts of bellflower, 6 parts of Peucedanum, 6 parts of winter melon seeds, 6 parts of hops 6 servings of ebony plum, 1 serving of Shujincao, 3 servings of papaya, and 10 servings of white horse bone.

Embodiment 3

[0034] Example 3, raw material drug weight ratio: 20 parts of fig leaves, 10 parts of sarcophagus, 6 parts of bamboo yellow, 10 parts of aescin, 6 parts of bellflower, 10 parts of Peucedanum, 10 parts of wax gourd seeds, 10 parts of hops 10 parts of black plum, 2 parts of Shujincao, 6 parts of papaya, 20 parts of white horse bone.

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PUM

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Abstract

The invention discloses a postoperative medicament for neurosurgery and a preparation method for the postoperative medicament. The preparation method is characterized by comprising the following steps: (1) extracting volatile oil from ficus virens, tabasheer, Chinese waxgourd seeds, glabrous sarcandra herb, beefwood-like clubmoss herb and radix platycodi coarse powder by using a steam distillation method respectively, collecting and mixing the volatile oil for standby, and remaining residues for use; (2) uniformly mixing paris polyphylla, serissa serissoides, radix peucedani, dark plum fruits, humulus lupulus, papayas and the residues obtained in the step 1, adding water with the amount 10 times of the total amount of the paris polyphylla, the serissa serissoides, the radix peucedani, the dark plum fruits, the humulus lupulus, the papayas and the residues obtained in the step 1, performing decoction twice for 1 hour each time, mixing decoction, standing the mixed decoction, adding 95 percent ethanol with the amount 3 to 4 times of that of liquid medicine into the decoction, standing the mixed solution for 15 minutes, performing centrifugation for 20 minutes at speed of 3,000rpm / min, extracting clear liquid, and performing concentration and spray drying to obtain an initial material; (3) spraying the volatile oil obtained in the step (1) into the initial material obtained in the step (3), enabling the initial material to pass through a 60-mesh sieve, and performing capsulation. Clinical experiments show that the postoperative medicament can be used for relieving postoperative pain, and has the characteristics of good curative effects, high safety and high clinical application and popularization value.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to postoperative medication for neurosurgery and a preparation method thereof. Background technique [0002] Pain is an unpleasant subjective sensory and emotional experience associated with tissue damage or potential damage. It contains two components of pain sensation and pain response. Pain sensation refers to the human's feeling of pain, which is unique to human beings. Pain can provide an alarm signal when the body is threatened, so that the body can respond quickly to noxious stimuli. Pathological pain can be divided into inflammatory pain and neuropathic pain according to different causes, which can be produced in both body and visceral tissues. Inflammatory pain refers to pain that occurs when inflammation is caused by peripheral tissue damage caused by trauma, bacterial or viral infection, and surgery, including hyperalgesia, allodynia, spontaneous pain, and s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K36/74A61P43/00
Inventor 于宗光孙晓艳
Owner CHONGQING TIANYI HENGHUA TECH CO LTD