Multi-mode photoacoustic imaging method combined with limited angle X ray imaging and ultrasonic imaging

A technology of photoacoustic imaging and ultrasonic imaging, which is applied in the fields of biomedicine and image processing, and can solve the problems of low quality of photoacoustic imaging images.

Inactive Publication Date: 2014-06-04
NANJING UNIV
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Problems solved by technology

[0004] Purpose of the invention: The technical problem to be solved by the present invention is to provide a multi-mode photoacoustic

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  • Multi-mode photoacoustic imaging method combined with limited angle X ray imaging and ultrasonic imaging
  • Multi-mode photoacoustic imaging method combined with limited angle X ray imaging and ultrasonic imaging
  • Multi-mode photoacoustic imaging method combined with limited angle X ray imaging and ultrasonic imaging

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Embodiment Construction

[0022] The invention solves the problem of low imaging quality of photoacoustic imaging by adding effective information of limited-angle X-ray imaging and ultrasonic images in the process of photoacoustic imaging reconstruction.

[0023] Such as figure 1 As shown, the present invention discloses a multi-mode photoacoustic imaging method combining limited-angle X-ray imaging and ultrasonic imaging, comprising the following steps:

[0024] Step 1, placing an X-ray emitter and a receiver above and below the target tissue, collecting X-ray projection data and reconstructing to obtain a limited-angle X-ray image of the tissue;

[0025] Step 2, placing an ultrasound probe on one side of the target tissue, transmitting ultrasound signals into the tissue and reconstructing ultrasound images according to the received ultrasound signals;

[0026] Step 3: Use laser light to irradiate one side of the tissue to produce photoacoustic effect, use ultrasonic sensor to receive signal on the o...

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Abstract

The invention discloses a multi-mode photoacoustic imaging method combined with limited angle X ray imaging and ultrasonic imaging. The multi-mode photoacoustic imaging method includes the following steps that an X ray emitter and a receiver are arranged above and below a target organization respectively, X ray projection data are collected and a limited angle X ray image obtaining the organization is reconstructed; an ultrasonic probe is arranged on one side of the target organization and emits ultrasonic signals to the inside of the organization and reconstructs an ultrasonic image according to the received ultrasonic signals; laser irradiating is carried on one side of the organization to generate the optoacoustic effect, an ultrasonic sensor is used for receiving the signals on the other side of the organization and a photoacoustic image is reconstructed according to the received signals; according to the photoacoustic image, the X ray image and the ultrasonic image are rectified; a multi-mode photoacoustic imaging result is obtained through reconstruction by being combined with the rectified X ray image and the rectified ultrasonic imaging result. The features that X ray imaging and ultrasonic imaging are good in imaging quality and high in resolution in individual imaging planes are utilized in the multi-mode photoacoustic imaging method, the image quality of photoacoustic imaging is improved and innovativeness is obtained.

Description

technical field [0001] The invention relates to the fields of biomedicine and image processing, in particular to a multi-mode photoacoustic imaging method combined with limited-angle X-ray imaging and ultrasonic imaging. Background technique [0002] Photoacoustic imaging technology is a new imaging mode that inverts the tissue structure according to the light absorption distribution of biological tissues. It can select the appropriate excitation light wavelength according to the optical absorption characteristics of the target to be measured, and can quantitatively measure the physiological parameters related to optical absorption. , and can observe the advanced functional activities of organisms without any damage and provide high-resolution and high-contrast tissue tomographic images in all directions. It combines the high contrast of pure optical imaging technology and the advantages of high sensitivity, high resolution and high penetration depth of pure ultrasonic imagi...

Claims

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Application Information

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IPC IPC(8): A61B6/00A61B8/00
Inventor 袁杰朱毅张星封婷李文超顾鹏储哲琪温馨曹萌梁澄宇刘晓峻
Owner NANJING UNIV
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