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A kind of probiotic microecological tablet and preparation method thereof

A probiotic micro-ecology, probiotic technology, applied in pharmaceutical formulations, medical raw materials derived from bacteria, medical preparations containing active ingredients, etc. The effect of intestinal flora, diverse bacterial species and high nutritional value

Active Publication Date: 2016-06-01
吉林省顺兴堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commercially available probiotic microecological preparations are mainly solid granules or capsules, and most of the probiotic powders contained in them are processed from a single strain of bacteria powder and auxiliary materials after compounding. , the vitality of the bacteria decreased, which was not enough to achieve the expected health effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1) Preparation of probiotic starter

[0028] ① Preparation of bifidobacteria

[0029] Inoculate the frozen Bifidobacterium adolescent powder into MRS lactose medium, culture at 37°C for 24 hours, and the microscopic examination conforms to the standard form of bifidobacteria, and the growth state is good. Inoculate 3% of the inoculum into MRS lactose medium For activation, culture at 37°C for 24 hours and save for later use.

[0030] ② Preparation of Kefir starter

[0031] Use skim milk powder to make 10% skim milk solution, after sterilizing at 115°C for 30 minutes, cool to 25°C, inoculate kefir grains with 0.1% of the volume of skim milk, ferment at 23°C for 18 hours and store for later use .

[0032] 2) Mixed fermentation

[0033] Take concentrated whey protein 10g, glucose 6.7g, yeast powder 3.8g, calcium carbonate 3.4g, magnesium sulfate 0.2g, manganese sulfate 0.015g, whey powder 14g, inulin 2.5g, ginseng polysaccharide 0.5g, soybean oligosaccharide 1g, add d...

Embodiment 2

[0040] 1) Preparation of probiotic starter

[0041] ① Preparation of bifidobacteria

[0042] Inoculate the frozen Bifidobacterium adolescent powder and Bifidobacterium infantis powder into MRS lactose medium respectively, culture at 37°C for 24 hours, and the microscopic examination conforms to the standard form of Bifidobacterium, and the growth state is good. 5%, were inoculated in MRS lactose medium for activation, 37 ℃, cultured for 20h. Mix Bifidobacterium adolescentis and Bifidobacterium infantis in a volume ratio of 1:1, and save for future use.

[0043] ② Preparation of Kefir starter

[0044] Use skim milk powder to make 10% skim milk solution, after sterilizing at 115°C for 30 minutes, cool to 23°C, inoculate kefir direct-throwing starter at 0.3% of the volume of skim milk, and ferment at 26°C Save for later use after 16 hours.

[0045] 2) Mixed fermentation

[0046]Take concentrated whey protein 18g, glucose 5g, yeast powder 4.29g, calcium carbonate 4.0g, magnes...

Embodiment 3

[0053] 1) Preparation of probiotic starter

[0054] ① Preparation of bifidobacteria

[0055] The frozen Bifidobacterium adolescent powder, Bifidobacterium longum powder and Bifidobacterium infantis powder were respectively inoculated in MRS lactose medium at 37°C. After culturing for 24 hours, the standard form of Bifidobacterium was found by microscope inspection. The growth state is good, according to the inoculum size of 6%, inoculated in MRS lactose medium for activation, 37 ℃, cultured for 20h. Mix Bifidobacterium adolescentis, Bifidobacterium longum and Bifidobacterium infantis in a volume ratio of 2:1:1, and store for later use.

[0056] ② Preparation of Kefir starter

[0057] Use skim milk powder to prepare 10% skim milk solution, after sterilizing at 115°C for 20 minutes, cool to 20°C, inoculate 0.5% of the volume of skim milk with kefir starter, and ferment at 28°C Save for later use after 14 hours.

[0058] 2) Mixed fermentation

[0059] Take concentrated whey ...

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PUM

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Abstract

The invention provides a probiotics micro-ecological tablet and a preparation method of the probiotics micro-ecological tablet, and belongs to the technical field of health food and processing. The probiotics micro-ecological tablet is prepared from the following components by weight percent: 90-98% of probiotics powder, 1-9% of fructo-oligose, and 0.1-1% of magnesium stearate. The preparation method of the probiotics micro-ecological tablet comprises the steps described as follows: activating bifidobacterium, and preparing a Kefir fermenting agent; carrying out mixed fermentation, cryoconcentration drying, mixing and tabletting on the bifidobacterium and the Kefir fermenting agent to obtain the probiotics micro-ecological tablets, wherein the mixed fermentation is specifically described as follows: inoculating probiotics mixed culture, and fermenting for 16-24 hours at 28-36 DEG C, and the ratio of the Kefir fermenting agent to the bifidobacterium in the mixed culture is (1-3):1. According to the probiotics micro-ecological tablet and the preparation method of the probiotics micro-ecological tablet, which are provided by the invention, the Kefir fermenting agent and the bifidobacterium are subjected to high-density mixed fermentation, the cultures are various, the storage of the probiotics micro-ecological tablet is stable, and the viable count in the probiotics micro-ecological tablet is respectively up to more than 2000 million cfu / g; the digestive capability can be improved, and the planting capability of probiotics in the intestinal canal is also enhanced; the probiotics micro-ecological tablet has the characteristics of high nutritive value, special flavor and the like.

Description

technical field [0001] The invention relates to a probiotic microecological tablet and a preparation method thereof, belonging to the technical field of health food and processing. Background technique [0002] As a kind of probiotic microecological preparation, probiotic microecological tablets have the functions of adjusting intestinal flora, improving the microecological balance of the human body, and inhibiting the growth and reproduction of harmful pathogenic microorganisms in the human body. The active ingredients in the probiotic microecological tablet are live probiotics. Currently, common probiotics include lactic acid bacteria, bifidobacteria, Lactobacillus bulgaricus, and Streptococcus thermophilus. At present, the commercially available probiotic microecological preparations are mainly solid granules or capsules, and most of the probiotic powders contained in them are processed from a single strain of bacteria powder and auxiliary materials after compounding. , ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00A61K35/741A61K35/745A61P1/12A61P1/10A61P37/04
CPCA23L29/30A23L33/135A23V2002/00A61K35/74A23V2200/30
Inventor 张铁华张欣宇田木钟姝凝杜志阳
Owner 吉林省顺兴堂药业有限公司
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