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Triclosan-free antibacterial soap

An anti-bacterial cleaning and anti-bacterial technology, applied in the direction of medical preparations containing active ingredients, skin care preparations, cosmetics, etc., can solve problems such as concerns about effects

Inactive Publication Date: 2014-08-20
RUBBERMAID COMMERCIAL PRODUCTS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also concerns about the effects of triclosan on humans

Method used

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  • Triclosan-free antibacterial soap
  • Triclosan-free antibacterial soap
  • Triclosan-free antibacterial soap

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0025] The antibacterial properties of Composition A (the triclosan-free cleaning composition of the present invention) were evaluated using an in vitro time-kill method test. The composition of the triclosan-free cleaning composition of the present invention is as follows:

[0026]

[0027] Composition A was tested for its ability to reduce E. coli and S. aureus bacterial populations. The reduction of each species from the initial population was calculated after exposure to the product for 15 seconds, 30 seconds, 1 minute or 5 minutes. In this example, the cleaning composition of the present invention was evaluated at a concentration of 99% by volume. Composition B (soap containing triclosan) was also evaluated using the same protocol and was essentially the same composition as composition A except for the addition of 0.3 wt% triclosan. Composition A and Composition B both had a pH of about 4.5. The findings of the study are summarized below.

[0028]

[0029] Surpr...

example 2

[0031] The antibacterial properties of the inventive composition A (triclosan-free cleaning product) from Example 1 were evaluated using a quantitative suspension test performed according to European standard EN1040 to evaluate basic bactericidal properties in chemical disinfectants and bactericides active. Compositions of the invention were tested for their ability to reduce S. aureus and Pseudomonas aeruginosa bacterial populations. In this example, the cleaning composition of the present invention was evaluated at a concentration of 80% by volume. Bacterial cells were incubated in dilutions of the test product in water for 15 seconds, 30 seconds, 1 minute or 5 minutes. The test product was then neutralized with a solution of 3.0% Tween 80, 0.3% lecithin, 0.1% histidine and 0.5% sodium thiosulfate in tryptone soy broth. The reduction of each species from the initial population was calculated after tiling. The same protocol was also used to evaluate Composition B, which is...

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PUM

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Abstract

Disclosed herein is an antibacterial cleansing composition. The cleansing composition is free of triclosan and comprises lactic acid / lactate and ethyl alcohol. Lactic acid / lactate is present in the composition in an amount of about 5 weight percent (wt %) to about 15 wt %, based on the total weight of the composition. Ethyl alcohol is present in an amount of about 1 wt % to about 20 wt %, based on the total weight of the composition. The pH of the composition is about 4 to about 5. The triclosan-free cleansing composition according to the invention has broad spectrum antibacterial activity that equals or even surpasses comparable formulations containing triclosan.

Description

technical field [0001] The present invention relates to antibacterial liquid cleansing compositions suitable for use in personal care products. The antibacterial liquid cleansing composition of the present invention comprises lactic acid / lactate and ethanol and is free of triclosan. The antibacterial liquid cleansing compositions of the present invention exhibit broad spectrum antibacterial activity and are as effective at eliminating bacterial contamination as comparable formulations containing triclosan. Background technique [0002] Antimicrobial liquid cleaning products, such as antibacterial soaps and hand sanitizers, have exploded in popularity over the past decade and are now a multi-billion dollar industry. These antibacterial cleaners were once largely confined to medical settings. However, in recent years, vicious outbreaks of bacterial infections (including Escherichia coli and Listeria monocytogenes) in the general population have intensified consumer demand fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/365A61Q17/00A61Q19/10
CPCA61K8/34A61K2800/30A61Q19/10A61Q17/005A61K8/365
Inventor 伊范·韦尔默郎玛格丽特·E·比斯尔约翰·范卡斯尔
Owner RUBBERMAID COMMERCIAL PRODUCTS