Culture media for stem cells

A culture medium and stem cell technology, applied in cell culture medium, cell culture active agent, pancreatic cells, etc., can solve the problem of not establishing a long-term culture system to maintain the differentiation potential phenotype and genome integrity of human epithelial stem cells
CN104024401AActive Publication Date: 2014-09-03KONINK NEDERLANDSE AKADE VAN WETENSCHAPPEN
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
KONINK NEDERLANDSE AKADE VAN WETENSCHAPPEN
Publication Date
2014-09-03

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Abstract

Culture media and methods for expanding and differentiating populations of stem cells and for obtaining organoids. Expanded cell populations and organoids obtainable by methods of the invention and their use in drug screening, toxicity assays and regenerative medicine.
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Description

[0001] All documents cited herein are incorporated by reference in their entirety. technical field

[0002] The present invention is in the field of stem cell culture media and methods, in particular culture media and methods for expanding stem cell populations, such as human epithelial stem cell populations. Background technique

[0003] There are great concerns about the media and methods used to expand stem cell populations. Stem cell populations have many uses. For example, stem cells and their differentiated progeny can be used in cell testing, drug screening and toxicity testing. Stem cells also show promise for cell-based therapy, for example in regenerative medicine for the treatment of damaged tissue. They are also used as a source of differentiated cells for transplantation purposes, such as transplantation of pancreatic beta cells for the treatment of diabetes, etc. Furthermore, efficient cell culture media are important to provide and maintain cell populations...

Claims

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