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Medicament composition for treating wound fester and preparation method thereof

A composition and drug technology, applied in the field of medicine, can solve problems such as the treatment of wound ulcers that have not been mentioned, and achieve the effect of promoting accelerated healing, high safety, and low irritation

Active Publication Date: 2014-09-10
JIANG SU PHARMAMAXCORP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0025] The above-mentioned several existing patents using pyruvate describe the method of using pyruvate to inhibit the generation of active oxygen to treat a series of diseases, but there is no mention of using maltodextrin, pyruvate compounds, and vitamin C as the basic active components to treat wound ulcers

Method used

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  • Medicament composition for treating wound fester and preparation method thereof
  • Medicament composition for treating wound fester and preparation method thereof
  • Medicament composition for treating wound fester and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1 Preparation of ointment of the pharmaceutical composition of the present invention

[0067] prescription:

[0068] Material

Dosage (g)

Maltodextrin

41

Pyruvate

0.5

Vitamin C

10

Glycerin

17

Ketoglutarate

0.5

purified water

31

[0069] Process:

[0070] 1. Dissolve the prescription amount of glycerin, vitamin C, pyruvic acid, and ketoglutarate in the prescription amount of water, stir it evenly, and fully dissolve it.

[0071] 2. Slowly pour the solution of step 1 into the prescribed amount of maltodextrin, and stir well to a uniform paste state.

[0072] 3. Pour the paste of step 2 into a small-capacity paste filling machine, and fill the paste containing the pharmaceutical composition of the present invention.

Embodiment 2

[0073] Example 2 Preparation of ointment of the pharmaceutical composition of the present invention

[0074] prescription:

[0075] Material

Dosage (g)

Maltodextrin

50

Sodium pyruvate

0.3

Vitamin C

5

Glycerin

15

Ketoglutarate

0.2

purified water

29.5

[0076] Process:

[0077] 1. Dissolve the prescription amount of glycerin, vitamin C, sodium pyruvate, and ketoglutarate in the prescription amount of water, stir evenly, and fully dissolve it.

[0078] 2. Slowly pour the solution of step 1 into the prescribed amount of maltodextrin, and stir well to a uniform paste state.

[0079] 3. Pour the paste of step 2 into a small-capacity paste filling machine, and fill the paste containing the pharmaceutical composition of the present invention.

Embodiment 3

[0080] Example 3 Preparation of ointment of the pharmaceutical composition of the present invention

[0081] prescription:

[0082] Material

Dosage (g)

Maltodextrin

52

Potassium pyruvate

5

Vitamin C

3

Glycerin

6.6

Ketoglutarate

0.4

purified water

33

[0083] Process:

[0084] 1. Dissolve the prescription amount of glycerin, vitamin C, sodium pyruvate, and ketoglutarate in the prescription amount of water, stir evenly, and fully dissolve it.

[0085] 2. Slowly pour the solution of step 1 into the prescribed amount of maltodextrin, and stir well to a uniform paste state.

[0086] 3. Pour the paste of step 2 into a small-capacity paste filling machine, and fill the paste containing the pharmaceutical composition of the present invention.

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Abstract

The invention provides a medicament composition for treating wound fester and a preparation method thereof. The medicament composition contains three active components namely maltodextrin, pyranic acid compounds, vitamin C, medicinal auxiliary materials or carriers. The invention also provides a method for preparing ointments, powder and patch by using the medicament composition. The medicament composition disclosed by the invention has the technical effects as follows: when the medicament composition containing the three active components namely maltodextrin, the pyranic acid compounds and vitamin C is used for treating wound fester, the medicament composition can be used for initiating the chemotaxis of immune cells such as neutrophils and the like, has the comprehensive pharmacological effects of promoting metabolism, resisting oxidation and the like, and can be used for promoting accelerated healing of wounds; the medicament composition containing the three active components namely maltodextrin, the pyranic acid compounds and vitamin C can be used for meeting the combined utilization of various treatment methods; when the medicament composition containing the three active components namely maltodextrin, the pyranic acid compounds and vitamin C is used for treating wound fester, the medicament composition is small in irritation to patients and high in safety.

Description

Technical field [0001] The invention provides a pharmaceutical composition for treating wound ulcers and a preparation method thereof, and belongs to the technical field of medicine. Background technique [0002] Wound ulceration is caused by various injuries or diseases of peripheral blood vessels or unexplained causes of blood circulation in the limbs, and the occurrence of ischemia and hypoxia, which eventually leads to necrosis, ulceration, and even gangrene of the skin and subcutaneous tissues of the limbs, and the formation of long-lasting ulceration wounds. It is quite common in clinical practice. Generally speaking, it can be summarized into two types, namely arterial: usually caused by insufficient blood supply caused by stenosis or occlusion of the lumen, such as arterial embolism, thrombo-occlusive vessel and Raynaud’s syndrome; venous: usually due to Lumen obstruction caused by obstruction of reflux, such as varicose veins of the lower limbs, and deep vein thrombosis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/718A61P17/02A61K31/19A61K31/375
Inventor 蒋志君斯坦利·莱赫蒋罗茵陆小娟王群
Owner JIANG SU PHARMAMAXCORP