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A traditional Chinese medicine extract for treating bile reflux gastritis and its application

A bile reflux and reflux extraction technology is applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., to achieve the effects of less toxic and side effects, easy quality control, and obvious curative effects.

Active Publication Date: 2016-01-20
NANTONG FINC PHARMA CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no literature report that Diwu extract has biological activity in the treatment of bile reflux gastritis

Method used

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  • A traditional Chinese medicine extract for treating bile reflux gastritis and its application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The preparation of embodiment 1 Diwu extract

[0017] Put 800g of dried Diwu into a round-bottomed flask, extract twice with 75% (v / v) ethanol and 55% (v / v) ethanol under reflux, each time for 4 hours, and pour out the alcoholic extract. Combine 4 extracts, filter, recover ethanol and continue to concentrate to a thick paste, dry under reduced pressure at 70°C, pulverize into fine powder, and pass through a 100-mesh sieve to obtain Diwu extract.

Embodiment 2

[0018] The preparation of embodiment 2 Diwu extract

[0019] Put 1 kg of dried Diwu into a round bottom flask, extract twice with 85% (v / v) ethanol and 60% (v / v) ethanol under reflux, each time for 4 hours, and pour out the ethanol extract. Combine 4 extracts, filter, recover ethanol and continue to concentrate into a thick paste, freeze-dry, pulverize into fine powder, and pass through a 100-mesh sieve to obtain Diwu extract.

Embodiment 3

[0020] The preparation of embodiment 3 Diwu extract

[0021] Put 2kg of dried Diwu into a round-bottomed flask, extract twice with 80% (v / v) ethanol and 60% (v / v) ethanol under reflux, each time for 4 hours, and pour out the ethanol extract. Combine 4 extracts, filter, recover ethanol and continue to concentrate into a thick paste, freeze-dry, pulverize into fine powder, and pass through a 100-mesh sieve to obtain Diwu extract.

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Abstract

The invention discloses a traditional Chinese medicinal extract for treating bile reflux gastritis and belongs to the technical field of traditional Chinese medicine extraction. The traditional Chinese medicinal extract is alcohol extract of anemone flaccida, which is prepared by the following steps: putting anemone flaccida in an extraction device, and performing reflux extraction sequentially with 80-90% (v / v) ethanol and 55-60% (v / v) ethanol; mixing the extracts, filtering, reclaiming ethanol, concentrating to obtain thick paste, and drying. Since the traditional Chinese medicinal extract is prepared from single medicinal material, the quality can be easily controlled; furthermore, the extract has a remarkable curative effect on bile reflux gastritis, can be used for treating both symptoms and root causes, and hardly causes toxic or side effects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine extraction, and in particular relates to a traditional Chinese medicine extract for treating bile reflux gastritis and its application. Background technique [0002] Bile reflux gastritis is a chronic inflammation caused by biliary dysfunction, pyloric sphincter insufficiency, bile reflux from the duodenum into the stomach, alkaline bile affecting the pH in the stomach, and damage to the gastric mucosa. Clinically, it is more common in patients after subtotal gastrectomy. Modern medicine mainly uses drugs that promote gastric motility, drugs that combine bile salts, drugs that inhibit gastric acid, anti-Helicobacter pylori drugs, etc., or surgical methods, but there are unsatisfactory therapeutic effects, It is prone to problems such as drug dependence, while surgical treatment has the disadvantages of high treatment costs and great physical harm to patients. Bile reflux gas...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P1/04
Inventor 闫华
Owner NANTONG FINC PHARMA CHEM