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Application of rabdosia rubescens extract in preparation of hypoglycemic agent

A Rubescens rubescens extract and a Rubescens rubescens technology are applied in the field of medicine, can solve problems such as the application of Rubescens spp., which have never been seen before, and achieve the effects of a simple preparation method and rich raw materials

Inactive Publication Date: 2014-10-08
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many studies on Oridinus, there is no application of Oridinus extract in the preparation of hypoglycemic drugs so far.

Method used

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  • Application of rabdosia rubescens extract in preparation of hypoglycemic agent
  • Application of rabdosia rubescens extract in preparation of hypoglycemic agent
  • Application of rabdosia rubescens extract in preparation of hypoglycemic agent

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Embodiment Construction

[0006] The specific implementation of the present invention will be described in detail below in combination with specific situations.

[0007] The present invention is implemented in the following ways.

[0008] The application of the extract of Rubescens japonicus in the preparation of hypoglycemic drugs, the extract of Rubescens japonicus is that the extract of Rubescens japonicus is pulverized into a coarse powder passing through a 20-30 mesh sieve, and the petroleum ether of 10 times the weight of Bryony japonicus is added and refluxed Extract 2 times, 1 hour each time, discard the petroleum ether liquid, evaporate the petroleum ether from the herb residue of Dongling, add the residue of the herb of Dongling, soak in ethanol with 10 times the weight and mass concentration of Dongling grass for 0.5h, and extract by reflux for 3 times , 1 hour each time, filter, combine the filtrates, recover ethanol under reduced pressure until there is no alcohol smell, and concentrate to...

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Abstract

The invention relates to an application of a rabdosia rubescens extract in preparation of a hypoglycemic agent, effectively solving the problem of treatment pharmacy of hyperglycemia. According to the application of the rabdosia rubescens extract in preparation of the hypoglycemic agent, the extract is prepared by the steps of grinding rabdosia rubescens into coarse powder; carrying out reflux extraction with petroleum ether; discarding a petroleum ether liquid; volatilizing petroleum ether with rabdosia rubescens decoction dregs; soaking with ethanol, carrying out reflux extraction to obtain a filtrate; decompressing and recycling the filtrate till no alcohol taste is available; concentrating to obtain a concentrated liquid; adding distilled water to the concentrated liquid for dispersion so as to obtain a dispersion liquid containing 0.1 g / ml of crude drug; eluting an AB-8 type macroreticular resin column on which the dispersion liquid is put with distilled water; discarding a liquid; eluting with ethanol; discarding an ethanol liquid; eluting with ethanol again; decompressing an ethanol eluant to recycle ethanol; and drying to obtain the rabdosia rubescens extract. The rabdosia rubescens extract has hypoglycemic effects and is effectively used for preparing the hypoglycemic agent; and the application of the rabdosia rubescens extract in preparation of the hypoglycemic agent is realized.

Description

technical field [0001] The present invention relates to medicine, in particular to the application of an extract from Radix Ordobenicum in the preparation of hypoglycemic drugs. Background technique [0002] Donglingcao, also known as Binglingcao, is a perennial herb or subshrub of the Lamiaceae Fragrant Tea genus, a small shrub, and is a variety of the genus Lamiaceae Fragrant Tea, because its plants are as thin as cicada wings and have different shapes. Named after the butterfly-shaped icicles. The whole plant is covered with silver-white ice flakes, which will not fall when the wind blows, swaying with the wind, and sparkling after sunrise, showing a magical natural landscape and having a unique ornamental effect. It has the effects of clearing away heat and detoxification, reducing inflammation and relieving pain, invigorating the stomach and activating blood circulation. The medicinal part is the whole plant. Although there are various researches on Oridinus radix, t...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61P3/10
Inventor 苗明三苗艳艳王灿
Owner HENAN UNIV OF CHINESE MEDICINE
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