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A kind of preparation method of kidney tonifying traditional Chinese medicine preparation

A traditional Chinese medicine preparation and kidney-tonifying technology, which is applied in the direction of medical formulas, drug combinations, and medical preparations containing active ingredients, etc., can solve problems affecting production costs, high ethanol consumption, poor clarity, etc., and reduce production costs , improve the transfer rate, and be beneficial to the effect of environmental protection

Active Publication Date: 2018-04-13
JIUZHITANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the original process, the extracts of medicinal materials such as Astragalus membranaceus and Rehmannia glutinosa were refined using alcohol precipitation followed by filtration and separation. Not only were macromolecular substances such as tannin not removed but active ingredients such as polysaccharides were removed, the production cycle was long and the ethanol consumption The dosage is large, the cost is high, and there are hidden dangers in safe production. The prescriptions contain ginseng, velvet and other precious medicinal materials, especially the price of Junyao ginseng and velvet has been rising rapidly, which directly affects its production cost.
[0004] In addition, the original preparation method of Bushen Tonifying Oral Liquid also has the following problems: the viscosity of the medicinal liquid is high, the solid-liquid is difficult to separate, and the liquid preparation prepared from this medicinal liquid has precipitation after a long period of storage, and the clarity is not good.

Method used

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  • A kind of preparation method of kidney tonifying traditional Chinese medicine preparation
  • A kind of preparation method of kidney tonifying traditional Chinese medicine preparation
  • A kind of preparation method of kidney tonifying traditional Chinese medicine preparation

Examples

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Effect test

Embodiment 1

[0058] prescription:

[0059] Ginseng 120g, deer antler (crisp) 120g, bullwhip (crisp) 60g

[0060] Dog Whip (Crisp) 60g Astragalus 360g Angelica 120g

[0061] Cistanche 40g Actinolite (calcined) 120g Wolfberry 720g

[0062] Eucommia 240g Aconite (made) 180g Cuscuta 240g

[0063] Rehmannia glutinosa 240g Epimedium 480g Leek seeds 120g

[0064] Preparation method:

[0065] 1) Superfinely pulverize ginseng, deer antler, and dog whip into very fine powder <10µm, set aside,

[0066] 2) Astragalus and other medicinal materials are decocted with water for 3 times, the first time is 10 times the amount of water, decocted for 3 hours, the second time is 8 times the amount of water, decocted for 2 hours, the third time is 4 times the amount of water, decocted for 1 hour hours, combine the decoction, filter the plate and frame, concentrate the filtrate to a clear paste with a relative density of 1.04-1.06 (60°C), let it cool to 60°C,

[0067] 3) Step 2) Add 1% chitosan acetic acid...

Embodiment 2

[0070] Prescription: same as the prescription of embodiment 1.

[0071] Preparation method: 1) Superfinely pulverize ginseng, velvet antler, dog whip, and bullwhip into very fine powders <5µm, set aside,

[0072] 2) Astragalus and other medicinal materials are decocted with water for 3 times, the first time is 9 times the amount of water, decocted for 3 hours, the second time is 6 times the amount of water, decocted for 2 hours, the third time is 4 times the amount of water, decocted for 2 hours hours, combine the decoction, filter through gauze, concentrate the filtrate to a clear paste with a relative density of 1.04-1.06 (60°C), let cool to 70°C,

[0073] 3) Step 2) Add 1% chitosan acetic acid solution to the obtained clear paste, the amount of chitosan acetic acid solution added is 5.5% of the clear paste weight, stir well, cool to room temperature, let stand for 20 hours, and centrifuge in a tube centrifuge Separation and filtration, the centrifugal speed range is 15000r...

Embodiment 3

[0076] Prescription: same as the prescription of embodiment 1.

[0077] Preparation method: 1) Ginseng, velvet antler, dog whip, bullwhip, and angelica are superfinely pulverized into a very fine powder of <0.1µm, set aside,

[0078] 2) Astragalus and other medicinal materials are decocted twice with water, the first time is 8 times the amount of water, decocted for 2 hours, the second time is 6 times the amount of water, decocted for 2 hours, combined decoction, filtered through plate and frame, and the filtrate Concentrate to a clear paste with a relative density of 1.04-1.06 (60°C), let cool to 65°C,

[0079] 3) Step 2) Add 1% chitosan acetic acid solution to the obtained clear paste, the amount of chitosan acetic acid solution added is 5.0% of the clear paste weight, stir well, cool to room temperature, let stand for 24 hours, horizontal automatic centrifuge Centrifugal separation and filtration, the centrifugal speed range is 20000rpm, the filtrate is concentrated to an ...

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine preparation for invigorating the kidney. The method comprises: superfinely pulverizing precious and fine medicinal materials such as ginseng and velvet antler, carrying out water extraction on the remaining medicinal materials, adding a flocculation clarifier to the extract, filtering and separating after standing, and obtaining the After the liquid medicine is concentrated, it is mixed with the above-mentioned superfine pulverized ultrafine powder, and suitable auxiliary material preparations are added. On the one hand, the method of the present invention reduces the loss of active ingredients and the decomposition and changes of some ingredients, and improves the utilization rate of medicinal materials; Active ingredients such as polysaccharides. Compared with the traditional alcohol precipitation process, it saves energy and reduces emissions, reduces costs and increases production safety. At the same time, the solid preparation has the advantages of good stability, easy portability, transportation and storage.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a preparation method of a traditional Chinese medicine preparation for invigorating the kidney. Background technique [0002] Bushen Tonifying Oral Liquid and Bushen Tonifying Pills are formulated with ginseng, antler (crisp), bullwhip (crisp), dog whip (crisp), astragalus, angelica, cistanche, actinolite (calcined), medlar, Eucommia, Aconite (prepared), dodder, rehmannia glutinosa, epimedium, and chive seeds are a kidney-tonifying traditional Chinese medicine preparation, which is recorded in the National Compilation of Chinese Patent Medicine Standards Internal Medicine Kidney System Subvolume. Its effects are to invigorate qi and blood, warm the kidney and strengthen yang. For deficiency of qi and blood, deficiency of kidney qi, weak waist and knees, impotence and cold essence. [0003] In the original process, the extracts of medicin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8962A61P1/14A61K33/26A61K35/32A61K35/48
Inventor 朱丽袁莉谷陟欣黄胜颜冬兰卢捷刘淑妦郗瑞云
Owner JIUZHITANG