Beta-elemene 14-site ramification and application of beta-elemene 14-site ramification in treating atherosclerosis

A kind of technology of elemenol ester and compound, which is applied in the field of preparation of β-elemene 14-position derivatives and β-elemene 14-position derivatives
CN104119221AInactive Publication Date: 2014-10-29DALIAN YUANDA PHARMA TECH DEV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
DALIAN YUANDA PHARMA TECH DEV
Publication Date
2014-10-29
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the field of organic synthesis and medicinal chemistry, and particularly relates to a beta-elemene 14-site ramification (I) or (II), wherein R1 and R2 are defined in the specification. The invention also discloses a preparation method of the beta-elemene 14-site ramification and application of the beta-elemene 14-site ramification on the aspect of resisting atherosclerosis. The ramifications I and II are as shown in the specification.
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Description

technical field

[0001] The invention relates to the fields of organic synthesis and medicinal chemistry, in particular to a class of β-elemene 14-position derivatives. The invention also discloses the preparation method of these β-elemene 14-position derivatives and their anti-atherogenic properties. applications in sclerosis. Background technique

[0002] Cardiovascular and cerebrovascular diseases, including coronary artery disease and stroke, are the main fatal diseases in the world. In recent years, with the continuous improvement of people's living standards and changes in eating habits, the incidence rate has been increasing year by year. It is reported that 100 million people per year Sixty-seven million people died of cardiovascular disease. AS is the common pathophysiological basis of cardiovascular and cerebrovascular events and an important factor causing cardiovascular and cerebrovascular diseases and death. In recent years, studies have shown that the occurrenc...

Claims

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