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Pueraria flavonid medical application

The technology of total flavonoids of puerariae and medicine is applied in the field of medical use of total flavonoids of puerariae, which can solve the problems of increasing the incidence of endometrial cancer, breast and ovarian cancer and the like.

Inactive Publication Date: 2014-11-19
安徽九方制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term use of estrogen can cause serious side effects, such as increased incidence of endometrial, breast, and ovarian cancers

Method used

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  • Pueraria flavonid medical application
  • Pueraria flavonid medical application

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] (1). Standard model animal experiments

[0023] 1 Materials and methods

[0024] 1.1 Experimental animals

[0025] 42 female SPF grade SD rats, weighing (200±20) g, were provided by the Experimental Animal Center of Anhui Medical University.

[0026] 1.2 Drugs and main instruments

[0027] Pueraria total flavonoids were provided by Anhui Jiufang Pharmaceutical Co., Ltd., with a total flavonoid content >60%, product batch number: 120902; prednisone acetate was purchased from Zhejiang Xianju Pharmaceutical Co., Ltd., product batch number: 1211155; tibolone tablets were purchased from the Netherlands Aos Organon Company, product batch number: 270163; Lunar iDXA dual-energy X-ray bone densitometer was purchased from GE Company in the United States; E3000 universal material testing machine was purchased from Instron Company in the United Kingdom; IX71 optical microscope was purchased from Olympus in Japan company.

[0028] 1.3 Method

[0029] 1.3.1 Castration-induced os...

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Abstract

The invention relates to a pueraria flavonid medical application, which is the application of pueraria flavonid in medicine for treating osteoporosis, especially postmenopausal primary osteoporosis. The pueraria flavonid is an extract product extracted from kudzu vine and root through backflow by ethanol, and the general flavone content in the extract product is greater than 60%. The animal experiment of a surgical castration standard model shows that the pueraria flavonid has certain treatment effect to osteoporosis.

Description

1. Technical field [0001] The invention relates to the medical application of active ingredients in plant Chinese herbal medicine. Specifically, one is the medicine of kudzu root total flavonoids [0002] use. 2. Background technology [0003] Pueraria lobata is a wild plant that can be used both as medicine and food. It is usually used for its root or processed edible kudzu root powder or to extract medicinal active ingredients. [0004] The applicant applied for an invention patent (200610113893.6) of a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases on October 20, 2006. The composition has thirteen components, all derived from kudzu root. and expose the following methods. [0005] First, the applicant uses the known ethanol extraction method to prepare the extraction liquid from the root of Pueraria lobata root. After the extract is concentrated, it is loaded on a D101 macroporous adsorption resin column, and ethanol is eluted. Re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/488A61P19/10
Inventor 宫彤林赵守田欧阳汉霖王建礼杨林路大勇郅立平杨小梅李玉梅李亚男
Owner 安徽九方制药有限公司