Composition for resisting swine foot-and-mouth disease, freeze-dried powder, and preparation method and use of freeze-dried powder

Abstract

The invention discloses a composition for resisting swine foot-and-mouth disease, freeze-dried powder, and a preparation method and use of the freeze-dried powder, and belongs to the technical field of veterinary feed additives. The composition comprises, by weight, 95-100 parts of a swine foot-and-mouth disease-resistant yolk antibody and 1-5 parts of a swine foot-and-mouth disease-resistant transfer factor. The freeze-dried powder comprises, by weight, 95-97 parts of the swine foot-and-mouth disease-resistant yolk antibody, 1-2 parts of the swine foot-and-mouth disease-resistant transfer factor, 0.2-0.3 parts of an inactivator, 0.01-0.02 parts of an antiseptic and 2.05-3.6 parts of a heat-resistant freeze-dried protective agent, and has the advantages of low preservation conditions, long preservation time, high antibody titer and good biological activity. Through combined use of the swine foot-and-mouth disease-resistant yolk antibody and the swine foot-and-mouth disease-resistant transfer factor, the freeze-dried powder has effects of preventing and treating swine foot-and-mouth disease, improves swine immunity and survival rate, is convenient for use and has a low cost.

Description

technical field [0001] The invention specifically relates to an anti-foot-and-mouth disease composition for a feed additive, and also relates to an anti-foot-and-mouth disease freeze-dried powder as well as a preparation method and application thereof, belonging to the technical field of animal feed additives. Background technique [0002] Foot-and-mouth disease (FMD) is an infectious disease that is caused by foot-and-mouth disease virus (FMDV) and is characterized by blisters on the mouth and hooves of sick animals. Foot-and-mouth disease is characterized by acute onset and rapid spread. In addition to being transmitted through solid objects contaminated by infected animals, it can also be transmitted over long distances through the air in the form of aerosols. The morbidity rate can reach 100%. Piglets often die suddenly without symptoms, and the mortality rate can reach 100% when severe. Once the disease occurs, if the early eradication is delayed, the epidemic situati...

AI Technical Summary

Problems solved by technology

Once the disease occurs, if the early eradication is delayed, the epidemic will often expand rapidly, resulting in an unmanageable situation, and it is difficult to eradicate

Effective measures to control and exterminate porcine foot-and-mouth disease are to cull diseased pigs and suspected infected pigs, restrict animal movement and meat marketing, thus causing serious economic losses

[0003] The pig industry accounts for a relatively large share in my country's breeding industry. In 2009, only Henan Province produced 4.1032 million tons of pork. From this, it can be deduced that my country's annual meat production demand is quite large, and it is showing a rapid increase trend. However, pig farming There are also various diseases in the pig industry. In recent years, the continuous occurrence of pig foot-and-mouth disease has caused great economic losses to the pig industry.

[0004] At present, people use vaccines to immunize porcine foot-and-mouth disease. The early effect is better, but multiple vaccinations are required, the operation is troublesome, the cost is high, and it is easy to cause stress reactions in livestock and poultry. In addition, the vaccines have strict requirements for storage conditions. Refrigerate at low temperature, and expire at room temperature for a period of time

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