Novel application of prunus mume extract as effective component for resisting carbonylation

A technology of carbonylation reaction and active ingredients, which is applied in the field of green calyx plum extract as an anti-carbonylation active ingredient, and can solve problems such as undisclosed green calyx plum extract

Active Publication Date: 2014-12-03
JALA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has not been disclosed that the extract of Prunus viridis has anti-carbonylation effects

Method used

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  • Novel application of prunus mume extract as effective component for resisting carbonylation
  • Novel application of prunus mume extract as effective component for resisting carbonylation
  • Novel application of prunus mume extract as effective component for resisting carbonylation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The optimization of embodiment 1 Lvcalyx plum extraction condition

[0034] Take 10g of green calyx plum, use L9 (3 3 ) Orthogonal test (commonly used mathematical methods and computer programs for drug research, Guizhou Science and Technology Press, 1997) to optimize the extraction process, with solid-liquid ratio (A), ethanol solution concentration (B), and extraction time (C) as test factors . Orthogonal design experiments were carried out with the extraction rate as the index to optimize the extraction process conditions. The factor level design is shown in Table 1, and considering the production cost, the extraction time is generally not more than 2 hours. The results are shown in Table 1-3.

[0035] Extraction method: wash and dry the buds of Prunus chinensis, crush them, mix them with aqueous ethanol, extract at room temperature for a certain period of time, separate the extract, evaporate the solvent under reduced pressure, and then obtain the Prunus chinensi...

Embodiment 2

[0045] Wash and dry 100g of commercially available 100g of green calyx plum flower buds, crush them, mix them with 2L of 70% ethanol solution, extract at room temperature for 2 hours, separate the extract, and evaporate the ethanol solution under reduced pressure to obtain 13g of green calyx plum extract , after dissolving with deionized water, load the sample to the AB-8 resin packed column, sequentially elute with deionized water, 20% ethanol, 40% ethanol, 60% ethanol and 80% ethanol, collect the eluents respectively, and depressurize Ethanol and water were distilled off to obtain water elution sites, 20% ethanol elution sites, 40% ethanol elution sites, 60% ethanol elution sites, and 80% ethanol elution sites, respectively.

Embodiment 3

[0047] Wash and dry 50g of the commercially available buds of Prunus chinensis, crush them, mix them with 2.5L of 50% ethanol solution, extract at room temperature for 1 hour, separate the extract, distill deionized water under reduced pressure, and obtain the Prunus chinensis extract 16g, dissolved in deionized water, loaded onto AB-8 resin packed column, eluted with deionized water, 20% ethanol, 40% ethanol, 60% ethanol and 80% ethanol in sequence, collected eluents respectively, and reduced Ethanol and water were steamed under pressure to obtain water elution sites, 20% ethanol elution sites, 40% ethanol elution sites, 60% ethanol elution sites and 80% ethanol elution sites, respectively.

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Abstract

The invention relates to a novel application of a prunus mume extract as an effective component for resisting carbonylation. Experiments show that the prunus mume extract has the function of removing reactive carbonyl ingredients. The prunus mume extract can be made into various skin-caring cosmetic compositions and various preparations by being mixed with auxiliary materials and additives for the cosmetics, and has actual application values.

Description

technical field [0001] The invention relates to a new application of the plant extract, in particular to a new application of the green calyx plum extract as an effective component of anti-carbonylation reaction. Background technique [0002] Yin proposed the carbonyl stress aging theory for the first time, and believed that carbonyl stress is one of the core biochemical processes of biological aging (Yin D. Studies on age pigments evolving into a new theory of biological aging. Gerontology, 1995, 41:159-172.) . Modern research also shows that active carbonyl compounds participate in and initiate the aging process (Uchida K. Role of reactive aldehyde in cardiovascular diseases. Free Radic Biol Med, 2000, 28:1685-1696.). With age, the level of protein carbonylation increases steadily, which leads to the reduction and loss of protein and cell functions, accelerates the accumulation of senile pigments, initiates or promotes the physiological and pathological processes of senil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/08
Inventor 方兆华李慧夏增华
Owner JALA GROUP CORPORATION
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