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A traditional Chinese medicine composition for treating precocious puberty in children and its preparation method

A composition and precocious technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problem of lack of effective children's precocious puberty

Inactive Publication Date: 2018-09-04
THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinically, there is a lack of Chinese medicine preparations that are highly effective and have no side effects to treat children with precocious puberty of various syndromes.

Method used

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  • A traditional Chinese medicine composition for treating precocious puberty in children and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Prescription: Bupleurum 80g, Scutellaria baicalensis 50g, Tangerine peel 60g, Pinellia chinensis 80g, Poria cocos 80g, Fructus aurantii 60g, Zhuru 80g, Yinchen 80g, aconite 40g, Codonopsis 50g, Atractylodes macrocephala 80g, dried ginger 40g, silkworm 60g, soil turtle worm 40g, pangolin 30g, vinegar turtle shell 100g, vinegar roasted tortoise shell 100g, cicada slough 40g, angelica 100g, calcined oyster 100g, white peony root 100g, roasted licorice 50g, amomum 50g, cork 40g, yam 80g, ginkgo 50g, chicken dung vine 100. Rehmannia glutinosa 100g, Asparagus 100g, Gorgon 80g, Ophiopogon japonicus 100g, Schisandra 50g.

[0054]Preparation process: Take aconite, pangolin, vinegar turtle shell, vinegar-baked turtle shell, and calcined oyster, add 10 times of water and decocted twice for 1.5 hours; , combine the above-mentioned decoctions, concentrate under reduced pressure to a relative density of 1.20-1.25 (heat measurement at 50 °C), add ethanol to the alcohol content of 60%,...

Embodiment 2

[0056] Bupleurum 120g, Scutellaria 80g, tangerine peel 80g, Qing Pinellia 120g, Poria 120g, Citrus aurantium 80g, Bamboo Ru 120g, Yin Chen 120g, Aconite 70g, Codonopsis 100g, Fried Atractylodes 120g, Dried Ginger 60g, Silkworm 80g, Turmeric 60g, pangolin 40g, vinegar turtle shell 150g, vinegar roasted turtle shell 150g, cicada slough 60g, angelica 120g, calcined oyster 150g, white peony root 150g, licorice 80g, Amomum 80g, phellodendron 60g, yam 150g, ginkgo 80g, chicken feces vine 150g , Rehmannia 150g, Asparagus 150g, Gorgon 120g, Ophiopogon japonicus 150g, Schisandra 80g.

[0057] Preparation process: Take aconite, pangolin, vinegar turtle shell, vinegar-baked turtle shell, and calcined oyster, add 15 times of water to decoct twice, each time for 2 hours; the remaining medicinal materials, add 12 times of water to decoct twice, each time for 1 hour , combine the above-mentioned decoctions, concentrate under reduced pressure to a relative density of 1.20-1.25 (thermal measur...

Embodiment 3

[0059] Prescription: Bupleurum 160g, Scutellaria baicalensis 100g, tangerine peel 100g, Qing Pinellia 150g, Poria 150g, Citrus aurantium 100g, Zhuru 160g, Yinchen 140g, Aconite 100g, Codonopsis 150g, Atractylodes 150g, dried ginger 80g, 120g silkworm, and turtle Insect 80g, pangolin 60g, vinegar turtle shell 200g, vinegar roasted turtle shell 200g, cicada slough 80g, angelica 150g, calcined oyster 200g, white peony 200g, licorice 100g, Amomum 100g, phellodendron 100g, yam 160g, ginkgo 100g, chicken feces vine 200, Shudi 200g, Asparagus 200g, Gorgon 150g, Ophiopogon japonicus 200g, Schisandra 100g.

[0060] Preparation process: take vinegar turtle shell, vinegar-baked turtle shell, calcined oyster, add 10 times of water and cook twice for 2 hours each time; The medicinal materials of Codonopsis pilosula, Cicada slough and Schisandra chinensis were boiled twice with 12 times of water for 1 hour each time. The above-mentioned decoctions were combined, concentrated under reduced p...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating child precocious puberty. The traditional Chinese medicine composition is characterized by consisting of the following medicines in parts by weight: radix bupleuri, scutellaria baicalensis, dried tangerine or orange peel, rhizoma pinelliae preparata, poria cocos, fructus aurantii, caulis bambusae in taeniam, oriental wormwood, monkshood, codonopsis pilosula, bighead atractylodes rhizome, rhizoma zingiberis, stiff silkworm, ground beetle, manis pentadactyla, vinegar turtle, stir-frying tortoise plastron with vinegar, cicada slough, angelica sinensis, calcined oyster shell, white paeony root, honey-fried licorice root, fructus amomi, golden cypress, Chinese yam, ginkgo seed, Chinese fevervine herb and root, rehmannia glutinosa, radix asparagi, gorgon fruit, radix ophiopogonis and schisandra chinensis. The medicine has the effects on soothing the liver, tonifying the spleen, removing dampness, tonifying the kidneys and yin, reducing ministerial fire, reducing phlegm, resolving masses and eliminating stagnation, is suitable for treating the child precocious puberty with multiple syndrome types such as kidney yin deficiency, liver depression dampness-heat, phlegm-heat obstruction and the like, and is obvious in clinical treatment effect. The cure rate is over 55 percent, the total effective rate is over 95 percent, and the traditional Chinese medicine composition has the characteristics of good curative effect, short course of treatment, complete curative effect, no side effect and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating precocious puberty in children and a preparation method thereof. Background technique [0002] With the improvement of living standard and educational level and the change of social environment, children's precocious puberty is increasing year by year. Because of its serious impact on children's height and psychological state, it has been paid more and more attention by the society. According to the survey, the incidence rate of precocious puberty among children in my country is about 1%, and it is about 3% in some economically developed cities. Precocious puberty refers to an endocrine disease characterized by early pubertal development and abnormal growth and development in children. It is the most common endocrine disease in children. Precocious puberty refers to the appearance of secondary sexual characteris...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P5/24A61K35/64A61K35/36A61K35/586A61K35/618
Inventor 朱宗敏谷民举陶琳璐闫孝军鲁兵
Owner THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM