System for determining the type of bleeding profile of a patient's gastrointestinal tract over time

Abstract

A device, system and method for the detection of bleeding inside the GI tract include irradiating the bodily fluids at different narrow band wavelengths as the device moves along the GI tract, detecting over time the absorbance or transmittance signals or measuring absorbance or transmittance spectra of the in- vivo fluids that pass through the sensing head of the device, processing the detected data, determining blood concentration over time and displaying blood concentration over time. The diagnostic device includes a housing with a gap that remains in contact with bodily fluids and through which the fluids may pass, and a sensing head comprising at least three LEDs on one side of the gap, each LED irradiating the bodily fluids at a different narrow band wavelength, and a light detector positioned at the opposite side of the gap and facing the LEDs, for detecting light which passes through the in-vivo bodily fluids.

Description

technical field [0001] The present invention relates to the field of in vivo detection. In particular, the present invention relates to devices, systems and methods for in vivo detection of bleeding in the gastrointestinal (GI) tract. Background technique [0002] Internal bleeding can occur due to different diseases in the body and in different locations along the gastrointestinal (GI) tract. This may indicate different pathologies occurring at those locations. For example, bleeding in the esophagus may be due to esophagitis in the esophagus or due to ruptured varices. Stomach ulcers, as well as duodenal ulcers, can cause bleeding. And, in the lower gastrointestinal tract, colorectal cancer can cause occult bleeding. Therefore, early detection of bleeding along the GI tract is critical for better treatment of many patients. [0003] Several devices and methods for detecting bleeding in the gastrointestinal tract are disclosed in the prior art. For example, an endoscop...

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Problems solved by technology

[0008] However, the above-mentioned device disclosed in WO 2010 / 086859 has several drawbacks, such as a limited number of LEDs (preferably four), which does not allow distinguishing between blood and other substances found in body fluids of the gastrointestinal tract, such as at 600nm and Chlorophyll with the same absorption band as blood at 700nm

[0009] Recently, it was found that the LED located in the sensor head also has the problem of relatively wide illumination angle

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