Animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas

A hyperpolarized, animal-based technology, applied in applications, medical science, sensors, etc., to achieve the effect of reducing the number of washes, ensuring protection, and shortening the time
CN104287731AActive Publication Date: 2015-01-21WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
Publication Date
2015-01-21

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Abstract

The invention discloses an animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas. The animal expiration device for the MRI of the lung hyperpolarization gas is characterized in that a computer is connected with a pressure sensor through an I / O (input / output) interface, one end of a gas circuit pipeline is connected with the pressure sensor, one end of a first electromagnetic valve is connected with a gas inflow port of a second electromagnetic valve, one end of the second electromagnetic valve is connected with a gas inflow port of a third electromagnetic valve, the second electromagnetic valve is respectively connected with a gas inflow port of a fifth electromagnetic valve and a gas exhaust port of a sixth electromagnetic valve, a gas exhaust port of the third electromagnetic valve is connected with a gas inflow port of carbon dioxide adsorbent, a gas exhaust port of the carbon dioxide adsorbent is connected with a gas inflow port of a forth electromagnetic valve, a mini vacuum pump is respectively connected with a gas inflow port of the sixth electromagnetic valve and a gas inflow port of a seventh electromagnetic valve, and a gas exhaust port of the seventh electromagnetic valve is communicated with the atmosphere. The animal expiration device for the MRI of the lung hyperpolarization gas is convenient to control, reduces time of exhaling the hyperpolarization gas of an animal lung, decreases the number of times of using the hyperpolarization gas to wash the animal lung, reduces anoxic time of an animal, and improves signal intensity of the hyperpolarization gas in the animal lung.
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Description

technical field

[0001] The invention belongs to the field of hyperpolarized gas magnetic resonance imaging (MRI) or spectroscopy (NMR), and more specifically relates to a device for controlling animal exhalation during the hyperpolarized gas MRI process of animal lungs, which can effectively enhance animal lung gas Signal, reducing the time of animal hypoxia, while reducing the waste of hyperpolarized gas. It is especially suitable for controlling the breathing of animals in MRI or NMR studies of hyperpolarized gases in animal lungs. Background technique

[0002] Currently, imaging techniques clinically used for disease detection include X-ray fluoroscopy, computed tomography (CT), MRI and positron emission tomography (PET), etc., but in addition to MRI, other imaging techniques All have a certain amount of radioactivity and cannot be imaged multiple times in a short period of time. MRI has the advantages of no radioactivity and high resolution. However, due to the cavity ...

Claims

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