Animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas

A hyperpolarized, animal-based technology, applied in applications, medical science, sensors, etc., to achieve the effect of reducing the number of washes, ensuring protection, and shortening the time

Active Publication Date: 2015-01-21
WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] Aiming at the problems described above in the field of hyperpolarized gas MRI application of animal lungs at present, the object of the present invention is to provide an animal exhalation device for lung hyperpolarized gas imaging

Method used

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  • Animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas
  • Animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas
  • Animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas

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Embodiment 1

[0027] according to figure 1 , figure 2 , image 3 It can be seen that an animal exhalation device for lung hyperpolarized gas MRI includes a computer 1, an I / O interface 2, an analog switch 3, a first solenoid valve 5, a pressure sensor 4, a second solenoid valve 6, The third solenoid valve 7, the carbon dioxide adsorbent 8, the fourth solenoid valve 9, the gas recovery bag 10, the fifth solenoid valve 11, the sixth solenoid valve 12, the seventh solenoid valve 13, the miniature vacuum pump 14, the gas pipeline 15, and more Strand electronic wire 16. It is characterized in that: the computer 1 is connected to the pressure sensor 4 through the I / O interface, and the air pipeline 15 is divided into two paths after the gas pipeline 15 is connected from the animal lung, and one end of the gas pipeline 15 is connected to the pressure sensor 4, and the gas pipeline 15 is connected to the pressure sensor 4. The other end of the pipeline 15 is connected to the inlet port of the fi...

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Abstract

The invention discloses an animal expiration device for MRI (magnetic resonance imaging) of lung hyperpolarization gas. The animal expiration device for the MRI of the lung hyperpolarization gas is characterized in that a computer is connected with a pressure sensor through an I / O (input / output) interface, one end of a gas circuit pipeline is connected with the pressure sensor, one end of a first electromagnetic valve is connected with a gas inflow port of a second electromagnetic valve, one end of the second electromagnetic valve is connected with a gas inflow port of a third electromagnetic valve, the second electromagnetic valve is respectively connected with a gas inflow port of a fifth electromagnetic valve and a gas exhaust port of a sixth electromagnetic valve, a gas exhaust port of the third electromagnetic valve is connected with a gas inflow port of carbon dioxide adsorbent, a gas exhaust port of the carbon dioxide adsorbent is connected with a gas inflow port of a forth electromagnetic valve, a mini vacuum pump is respectively connected with a gas inflow port of the sixth electromagnetic valve and a gas inflow port of a seventh electromagnetic valve, and a gas exhaust port of the seventh electromagnetic valve is communicated with the atmosphere. The animal expiration device for the MRI of the lung hyperpolarization gas is convenient to control, reduces time of exhaling the hyperpolarization gas of an animal lung, decreases the number of times of using the hyperpolarization gas to wash the animal lung, reduces anoxic time of an animal, and improves signal intensity of the hyperpolarization gas in the animal lung.

Description

technical field [0001] The invention belongs to the field of hyperpolarized gas magnetic resonance imaging (MRI) or spectroscopy (NMR), and more specifically relates to a device for controlling animal exhalation during the hyperpolarized gas MRI process of animal lungs, which can effectively enhance animal lung gas Signal, reducing the time of animal hypoxia, while reducing the waste of hyperpolarized gas. It is especially suitable for controlling the breathing of animals in MRI or NMR studies of hyperpolarized gases in animal lungs. Background technique [0002] Currently, imaging techniques clinically used for disease detection include X-ray fluoroscopy, computed tomography (CT), MRI and positron emission tomography (PET), etc., but in addition to MRI, other imaging techniques All have a certain amount of radioactivity and cannot be imaged multiple times in a short period of time. MRI has the advantages of no radioactivity and high resolution. However, due to the cavity ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055A61B19/00
CPCA61B5/055
Inventor 周欣阮伟伟李海东钟俭平孙献平叶朝辉刘买利
Owner WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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