Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of oral radix physochlainae solution

A technology of ginseng oral liquid and ethanol aqueous solution, which is applied in the field of preparation of Huashan ginseng oral liquid, can solve the problems of large side effects, complicated pathogenesis, etc., and achieve the effects of quick onset, remarkable curative effect, and convenient administration

Inactive Publication Date: 2015-04-08
津药达仁堂集团股份有限公司第六中药厂
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pathogenesis of the disease is very complicated, and there are various inducing factors. Western medicine mainly treats it with antibiotics, hormone drugs, β2 receptor stimulants, etc., with relatively large side effects.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of oral radix physochlainae solution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A preparation method of Huashan ginseng oral liquid, comprising the steps of:

[0018] (1) Take Huashan ginseng and grind it into a coarse powder, use 7 mass times the volume percentage concentration of 85% ethanol aqueous solution to reflux extract twice, each time for 2 hours, combine the extracts, filter, recover ethanol from the filtrate, and concentrate to 70 °C The relative density is 1.2, and the concentrated paste is obtained;

[0019] (2) Dilute the concentrated ointment with purified water at a mass ratio of 1:1, add ammonia water to make it alkaline to pH=9, obtain an alkalized dilution, extract 3 times with chloroform that is twice the volume of the alkalized dilution Once, the extract was obtained, the chloroform was reclaimed, and the ginseng extract was obtained by evaporating in a water bath until there was no chloroform smell;

[0020] (3) adding distilled water with 30 times the weight of the Huashan ginseng extract and 3 times of sucrose, and mixing ...

Embodiment 2

[0023] A preparation method of Huashan ginseng oral liquid, comprising the steps of:

[0024] (1) Take Huashan ginseng and grind it into a coarse powder, use 4 mass times the volume percentage concentration of 95% ethanol aqueous solution to reflux extract 3 times, each time for 1 hour, combine the extracts, filter, recover ethanol from the filtrate, and concentrate to 80 ° C The relative density is 1.3, and the concentrated paste is obtained;

[0025] (2) According to the ratio of 1:0.8 in mass ratio, dilute the concentrated ointment with purified water, add ammonia water to alkalinize to make pH=11, obtain alkalized diluent, extract 3 times with chloroform of alkalized diluent volume 3 times Once, the extract was obtained, the chloroform was reclaimed, and the ginseng extract was obtained by evaporating in a water bath until there was no chloroform smell;

[0026] (3) Add distilled water with 10 times the weight of the Huashan ginseng extract and 0.1 times of sucralose, mix...

Embodiment 3

[0029] A preparation method of Huashan ginseng oral liquid, comprising the steps of:

[0030] (1) Take Huashan ginseng and grind it into coarse powder, use 10 times by mass of 70% ethanol aqueous solution to reflux extract once, extract for 4 hours, filter the extract, reclaim ethanol from the filtrate, and concentrate to a relative density of 65°C. 1.03 to obtain a concentrated ointment; (2) dilute the concentrated ointment with purified water at a mass ratio of 1:1.5, add ammonia water to make pH = 8, and obtain an alkalized dilution, which is 0.5 times the volume of the alkalized dilution The chloroform was extracted 4 times to obtain the extract, the chloroform was recovered, and the ginseng extract was obtained by evaporating in a water bath until there was no chloroform smell;

[0031] (3) adding distilled water with 50 times the weight of the Huashan ginseng extract and 5 times of xylose, and mixing to make Huashan ginseng oral liquid. Example 4

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method of an oral radix physochlainae solution. The preparation method comprises the following steps of (1) smashing radix physochlainae to form coarse powder, carrying out reflux extraction by using an ethanol water solution to obtain an extracting solution, filtering to obtain filtrate, recovering ethanol from the filtrate, and concentrating to obtain concentrated paste; (2) diluting the concentrated paste with purified water, adding ammonia water to alkalize to obtain an alkalized diluent, extracting 2-4 times by using trichloromethane which is 0.5-3 times as much as the volume of the alkalized diluent to obtain an extracting solution, recovering trichloromethane, and volatilizing a water bath until no trichloromethane smell to obtain a radix physochlainae extract; and (3) adding distilled water which is 10-50 times as much as the mass of the radix physochlainae extract and a corrigent which is 0.1-5 times as much as the mass of the radix physochlainae extract, and uniformly mixing to prepare the oral radix physochlainae solution. Experiments prove that the oral radix physochlainae solution prepared by using the preparation method disclosed by the invention has a favorable asthma relieving effect. The oral radix physochlainae solution prepared by using the preparation method disclosed by the invention is high in effect taking speed, convenient to take, remarkable in curative effect and capable of simultaneously treating both symptoms and root causes, so that the requirements of extensive patients can be met. By using the preparation method, few labor hours are needed, and the transfer rate of effective components is high.

Description

technical field [0001] The invention belongs to the field of modernized traditional Chinese medicine pharmacy, and in particular relates to a preparation method of Huashan ginseng oral liquid. Background technique [0002] Asthma is a widespread and reversible airway narrowing disease caused by bronchial hyperresponsiveness caused by allergens or other factors. The clinical manifestations are recurrent chest tightness, wheezing, dyspnea, cough and other symptoms. Before the attack, there are often aura symptoms such as nasal congestion, sneezing, and itchy eyes. In severe cases, severe dyspnea and hypoxemia may occur within a short period of time, threatening life. There are about 2000-3000 deaths from asthma in the United States every year, and there is an increasing trend. In 2004, the Global Initiative for Asthma Prevention (GINA) estimated that there were about 300 million cases in the world, the prevalence of asthma in children and adults was about 3.3%-29% and 1.2%-2...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/81A61K9/08A61P11/06
Inventor 刘丹佟永领王金磊刘梦妮
Owner 津药达仁堂集团股份有限公司第六中药厂
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com