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Method for extracting carnosol from complete salvia

A technology of carnosol and sage, which is applied in the field of extracting natural active compounds, can solve the problems of low quality and yield, and can not effectively preserve the active ingredients of sage, so as to change the low added value, quality and Increased yield and good social benefits

Inactive Publication Date: 2015-04-22
浙江泰康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The extraction method of carnosol is traditionally extracted by using a lipophilic organic solvent, which has the problem of not being able to effectively preserve the original functional components of sage, and its quality and yield are low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] S1: cleaning, disinfection, and rinsing of the whole sage grass: washing in clean water, and disinfecting with 3% potassium permanganate solution, and then rinsing in clean water;

[0009] S2: Grinding and extracting the juice of sage: the slurry is ground to a thickness of 200 meshes;

[0010] S3: rough extraction of functional components: NaOH is added to the 5% aqueous ethanol solution, the pH value of the adjusted aqueous ethanol solution is 9.5, and the weight ratio of the aqueous ethanol solution and sage is 3:1, and extracted at 90° C. for 3 hours;

[0011] S4: organic solvent extraction: the crude extract is added to the polar solvent with the pH value of 5 times of weight and is extracted, and extracted at normal temperature for 10 hours;

[0012] S5: separation and purification: the extract is separated by membrane separation, column chromatography, and the detection of the functional component content and the yield of the extract is detected;

[0013] S6: va...

Embodiment 2

[0016] S1: cleaning, disinfection, and rinsing of the whole sage grass: washing in clean water, and disinfecting with 3% potassium permanganate solution, and then rinsing in clean water;

[0017] S2: Grinding and extracting the juice of sage: the slurry is ground to a thickness of 200 meshes;

[0018] S3: crude extraction of functional components: NaOH is added to the 5% aqueous ethanol solution, the pH value of the adjusted aqueous ethanol solution is 9.5, and the weight ratio of the aqueous ethanol solution and sage is 3:1, and extracted at 90° C. for 3 hours;

[0019] S4: organic solvent extraction: the crude extract is added in the polar solvent extraction with the pH value of 5 times of weights, and is extracted at normal temperature for 10 hours;

[0020] S5: separation and purification: the extract is separated by membrane separation, column chromatography, and the detection of the functional component content and the yield of the extract is detected;

[0021] S6: vacu...

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PUM

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Abstract

The invention discloses a method for extracting carnosol from complete salvia. The method comprises the following steps of cleaning, disinfecting and washing the salvia, grinding and juicing the salvia, crudely extracting functional components, extracting the functional components, separating and purifying the functional components, concentrating the functional components in vacuum and drying the functional components through vacuum freezing or spraying, and then the carnosol is obtained. The advanced film separation and column separation technologies are adopted, the original functional components of the salvia are effectively maintained, and the quality and yield of the carnosol are improved.

Description

technical field [0001] The present invention relates to a method for extracting natural active compounds from natural plants, in particular to a method for extracting carnosol from whole sage. Background technique [0002] Clary sage belongs to the genus Sage of the Lamiaceae family. It can treat menopausal disorders and breastfeeding during weaning. It can also be used as a bitter and stomachic medicine. , and promote bile secretion. It is also used as an antibacterial agent, an antiseptic, a gargle and cleanser for oral surgical wound infections, and a detergent for the treatment of various skin diseases, especially those caused by fungi. Clary sage extract carnosol has excellent calming and skin tightening effects, can promote the growth of scalp hair, increase black luster, and prevent excessive sweating. It is also effective for amenorrhea and dysmenorrhea; it helps to improve memory. [0003] The extraction method of carnosol is traditionally extracted by using a li...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D493/08
CPCC07D493/08
Inventor 陈林心
Owner 浙江泰康生物科技有限公司